Layer-by-layer sensor architecture of polymers and nanoparticles for electrochemical detection of uric acid in human urine samples

Sensitive and selective electrochemical determination of uric acid in urine based on ultrasmall iron oxide nanoparticles decorated urchin-like nitrogen-doped carbon

“…The UNC precursor is synthesized through the Friedel-Crafts reaction. Scheme 1 describes the mechanism of UA detection using the Fe x O y /UNC sensor [34]. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), mapping, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and other characterization methods are used to determine the morphologies, structures, and elemental distributions of the samples.…”

Hemin-Functionalized Microfluidic Chip with Dual-Electric Signal Outputs for Accurate Determination of Uric Acid

“…Continuous monitoring of UA molecule is of great significance to understand human metabolic state and provides a valuable window into healthcare. At present, various methods including colorimetric assay, fluorescence analysis, surface-enhanced Raman scattering, and electrochemical sensing have been developed for UA monitoring. Among these approaches, electrochemical sensing shows distinct advantages of fast response and high sensitivity. , However, some restrictions still exist in electrochemical sensing:(i) relatively low catalytic capacity of sensing interface; (ii) imprecise output of single-electric signal; (iii) independent sample treatment and analysis process.…”

“…3 Continuous monitoring of UA molecule is of great significance to understand human metabolic state and provides a valuable window into healthcare. At present, various methods including colorimetric assay, 4 fluorescence analysis, 5 surface-enhanced Raman scattering, 6 and electrochemical sensing 7 have been developed for UA monitoring. Among these approaches, electrochemical sensing shows distinct advantages of fast response and high sensitivity.…”

Chelating and Construction Effects on a Self‐Assembled Blend for Electrochemical Lead (II) Detection

“…Additionally, the blend of two polymers allows the adaptability of the sensing film with the proper selection of substituents of the main chain. [17,23,24] Constructions with polymers are commonly based on ion imprinting, layer-by-layer assemblies, self-assembled systems or drop casting techniques on the electrode surface. In this sense, accordingly to the group experience, screen printed sensors are easy to modify, userfriendly, and disposable.…”

“…Polymeric materials are very attractive for electrode modification due to their low cost, their ability to stick to other materials, their conductivity, electrical and adsorption properties. Additionally, the blend of two polymers allows the adaptability of the sensing film with the proper selection of substituents of the main chain [17,23,24] . Constructions with polymers are commonly based on ion imprinting, layer‐by‐layer assemblies, self‐assembled systems or drop casting techniques on the electrode surface.…”