Layered Copper Hydroxide Salts as Catalyst for the “Click” Reaction and Their Application in Methyl Orange Photocatalytic Discoloration

Abstract

The 1,2,3-triazoles are an important class of organic compounds that are found in a variety of biologically active compounds. The most usual and efficient methodology to synthetize these compounds is the Copper-catalyzed Azide–Alkyne Cycloaddition (CuAAC), preferably by use of click chemistry principles. Therefore, the development of simple, robust, easily accessible and efficient materials as catalysts for this kind of reaction is highly desirable. In this sense, layered hydroxide salts (LHS) emerge as an interesting alternative for the click reaction. Thus, we describe herein the preparation and characterization of copper (II) layered hydroxide salts and their application as catalysts for the CuAAC reaction under solvent-free conditions. This synthetic methodology of CuAAC reaction is attractive as it follows several concepts of green chemistry, such as being easy to perform, allowing purification without chromatographic column, the process forming no sub-products, affording the desired 1,2,3-traizoles in the specific 1,4-disubstituted position in high yield, and having a short reaction time. Moreover, the photocatalysis for the degradation of methyl orange was also highly efficient using the same catalyst.

Iron-Borophosphate Glass-Catalyzed Regioselective Hydrothiolation of Alkynes under Green Conditions

“…In addition, solvent-free reactions are attractive alternatives in organic synthesis and are considered an important contribution to the evolution of green chemistry [33,34]. Based on our interest in developing new sustainable materials and eco-friendly processes for organic reactions and material sciences [35][36][37][38][39][40], we describe herein the synthesis of a cheap and readily available iron-borophosphate glass and its application as a recyclable catalyst for the synthesis of vinyl sulfides.…”