LC Determination of Gallic Acid in Preparations Derived from Schinus terebinthifolius Raddi

Carvalho, M.G.; Freire, Fátima Duarte; Raffin, Fernanda Nervo; Aragão, Cícero Flávio Soares

doi:10.1365/s10337-009-1096-x

Cited by 16 publications

(16 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In both cases, the water was acidified with formic acid to pH 2.7. The retention times under both conditions were 5 min, although the phase with acetonitrile was slightly shorter (Carvalho et al, 2009).…”

Section: Resultsmentioning

confidence: 98%

Development of a rapid and simple HPLC-UV method for determination of gallic acid in Schinopsis brasiliensis

Fernandes

Batista

Medeiros

et al. 2015

Revista Brasileira de Farmacognosia

View full text Add to dashboard Cite

Revista Brasileira de Farmacognosia 25 (2015) 208-211 w w w . s b f g n o s i a . o r g . b r / r e v i s t a a b s t r a c tThe aim of this work was to develop and validate an analytical method for the identification of the chemical marker of Schinopsis brasiliensis Engl., Anacardiaceae. It would determine the total polyphenols and flavonoid content by spectrophotometric methodology in the dried extract of plant. The chromatographic profiles of S. brasiliensis were determined using HPLC-UV. The liquid chromatography method was conducted on a Phenomenex Gemini NX C18 column (250 × 4.6 mm, 5 m). The mobile phase consisted of 0.05% orthophosphoric acid: methanol. The flow rate was 1 ml/min and effluents were monitored at 271 nm. The retention time for gallic acid was 8.5 min. The described method has the advantage of being both rapid and easy. Hence it can be applied for routine quality control analysis of herbal preparation containing S. brasiliensis.

show abstract

Section: Resultsmentioning

confidence: 98%

Development of a rapid and simple HPLC-UV method for determination of gallic acid in Schinopsis brasiliensis

Fernandes

Batista

Medeiros

et al. 2015

Revista Brasileira de Farmacognosia

View full text Add to dashboard Cite

show abstract

“…Although it is necessary to confirm the results through well validated tests performed in mammalian cells, it probably indicates the absence of potential risks in inducing cancer and other genetic disorders in individuals under treatment with this plant (Ruiz et al, 1996). Evaluating the genotoxic potential of S. terebinthifolius extract in an in vitro assay, Carvalho et al (2009) observed that although the extract did not cause a direct break in the DNA structure, it showed potential to cause oxidative damage to DNA, as well as bacterial mutation.…”

Section: Toxicitymentioning

confidence: 99%

Schinus terebinthifolius Raddi: chemical composition, biological properties and toxicity

Carvalho

Melo

Aragão

et al. 2013

Rev. bras. plantas med.

105

View full text Add to dashboard Cite

RESUMO: Schinus terebinthifolius Raddi: Composição química, propriedades biológicas, e toxicidade. Schinus terebinthifolius Raddi é uma planta medicinal conhecida no Brasil como "aroeira da praia", utilizada na medicina popular como antitérmica, analgésica, depurativa e no tratamento de doenças do sistema urogenital. Por outro lado, a literatura científica relata que essa planta apresenta atividade antimicrobiana, anti-inflamatória, e antiulcerogênica. Essa revisão trata das principais propriedades biológicas e efeitos toxicológicos da aroeira da praia, além de uma abordagem sistemática acerca dos compostos que já foram encontrados nessa espécie, estando a maioria deles presente nos óleos essenciais.Palavras Chave: Schinus terebinthifolius, Anacardiaceae, componentes químicos, propriedades biológicas. ABSTRACT: Schinus terebinthifoliusRaddi is a medicinal plant known in Brazil as "aroeira da praia", which has been used in popular medicine as antipyretic, analgesic, depurative and in the treatment of diseases of the urogenital system. On the other hand, the scientific literature has reported that this plant has antimicrobial, anti-inflammatory and antiulcerogenic activity. This review addresses the main biological properties and toxicological effects of "aroeira da praia", in addition to a systematic approach of the compounds that were already found in this species, the great majority of which is present in the essential oils.

show abstract

“…[ 18 ] However, possible interference has been described. To increase the specificity and eliminate interferences, several methods using high-performance liquid chromatography (HPLC) have been described for the determination of GA and[ 19 20 21 ] EA,[ 22 23 24 ] both in herbal drugs and biological matrices. [ 25 ] Once, GA and EA are determined in fruit and to prove the suitability of the method developed, it is necessary to perform validation of the methodology to establish acceptable parameters as well as to determine the total amount of the main compounds that are appropriate for the quality control.…”

Section: Introductionmentioning

confidence: 99%

Chromatographic and spectrophotometric analysis of phenolic compounds from fruits of Libidibia ferrea Martius

Ferreira¹,

Fernandes²,

Silva³

et al. 2016

Phcog Mag

View full text Add to dashboard Cite

Background:Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz (Fabaceae) is a tree which is native to Brazil, widely known as “Jucá,” where its herbal derivatives are used in folk medicine with several therapeutic properties. The constituents, which have already been described in the fruit, are mainly hydrolysable tannins (gallic acid [GA] and ellagic acid [EA]).Objective:The aim of this study was to investigate the phenolic variability in the fruit of L. ferrea by ultraviolet/visible (UV/VIS) and chromatographic methods (high-performance liquid chromatography [HPLC]/high-performance thin layer chromatography [HPTLC]).Materials and Methods:Several samples were collected from different regions of Brazil and the qualitative (fingerprints by HPTLC and HPLC) and quantitative analysis (UV/VIS and HPLC) of polyphenols were performed.Results:The HPTLC and HPLC profiles allowed separation and identification of both major analytical markers: EA and GA. The chemical profiles were similar in a number of spots or peaks for the samples, but some differences could be observed in the intensity or area of the analytical markers for HPTLC or HPLC, respectively. Regarding the quantitative analysis, the polyphenolic content by UV/VIS ranged from 13.99 to 37.86 g% expressed as GA or from 10.75 to 29.09 g% expressed as EA. The contents of EA and GA by liquid chromatography-reversed phase (LC-RP) method ranged from 0.57 to 2.68 g% and from 0.54 to 3.23 g%, respectively.Conclusion:The chemical profiles obtained by HPTLC or HPLC, as well as the quantitative analysis by spectrophotometry or LC-RP method, were suitable for discrimination of each herbal sample and can be used as tools for the comparative analysis of the fruits from L. ferrea.SUMMARY The polyphenols of fruits of Libidibia ferrea can be quantified by UV/VIS and HPLCThe HPLC method was able to detect the gallic and ellagic acids in several samples of fruits of Libidibia ferreaThe phenolic profiles of fruits from Libidibia ferrea by HPTLC and HPLC were reproductible. Abbreviations used: HPTLC: high performance thin layer chromatography, HPLC: high performance liquid chromatography, UV-Vis: spectrophotometry

show abstract

LC Determination of Gallic Acid in Preparations Derived from Schinus terebinthifolius Raddi

Cited by 16 publications

References 6 publications

Development of a rapid and simple HPLC-UV method for determination of gallic acid in Schinopsis brasiliensis

Development of a rapid and simple HPLC-UV method for determination of gallic acid in Schinopsis brasiliensis

Schinus terebinthifolius Raddi: chemical composition, biological properties and toxicity

Chromatographic and spectrophotometric analysis of phenolic compounds from fruits of Libidibia ferrea Martius

Contact Info

Product

Resources

About