1995
DOI: 10.5271/sjweh.42
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Lead intoxication caused by skeletal disease

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Cited by 41 publications
(29 citation statements)
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“…In physiological and pathological states such as pregnancy, lactation, and osteoporosis, mobilization of lead from the bone reservoir may occur (8,14,15). In two case reports lead poisoning in thyrotoxicosis was described in formerly lead-exposed subjects (6,7).…”
Section: Discussionmentioning
confidence: 98%
See 1 more Smart Citation
“…In physiological and pathological states such as pregnancy, lactation, and osteoporosis, mobilization of lead from the bone reservoir may occur (8,14,15). In two case reports lead poisoning in thyrotoxicosis was described in formerly lead-exposed subjects (6,7).…”
Section: Discussionmentioning
confidence: 98%
“…In these cases treatment of hyperthyroidism has been shown to decrease blood lead concentrations (6,7). Lead intoxication was also observed in patients with skeletal diseases such as osteoporosis, and it was suspected that a moderately increased bone lead pool and skeletal disease may increase the risk of lead poisoning (8).…”
Section: Introductionmentioning
confidence: 98%
“…HRT, alone or combined, prevents bone resorption and increases the BMD in trabecular and cortical bones of women with and without metabolic bone disease (Berlin et al 1995;Gruber et al 1997;Webber et al 1995). This effect may lead to a decrease of lead mobilization from bone together with a reduction in blood lead levels.…”
Section: Discussionmentioning
confidence: 99%
“…Suspicion exists that the accumulation of lead in bone itself represents a risk factor for osteoporosis. Individual cases such as the subjects reported by Berlin et al (1995) who had occupational lead exposure, a bone fracture, and diagnosis of idiopathic osteoporosis provide some circumstantial evidence of such a relationship. Other evidence supporting the hypothesis that lead can directly damage bone includes observations of fetal and neonatal growth reduction and the development of osteopenia in experimental animals exposed to lead (Gruber et al 1997).…”
Section: Discussionmentioning
confidence: 99%
“…Under conditions in which the individual's body burden of lead is higher than that typical of the current environment, the predicted PbB concentrations could be dominated by PbBone stores. For example, Berlin et al (22) (33).…”
Section: Dose Response To Leadmentioning
confidence: 99%