Background and Objectives: Nurse Managers are required to apply leadership styles suited to the complicated and constantly changing healthcare system. This study aimed to compare the perceived and preferred perceptions of nursing personnel and managers toward leadership styles of nurse managers. Materials and Methods: This cross-sectional and analytical study was conducted on 341 subjects selected from nurse managers and staff employed in the teaching and treatment centers affiliated to YUMS, Yasuj, Iran. Data collection tool was the change, production, employee (CPE) model questionnaire, and data analysis was performed by Independent t-test. Results: The total score of preferred view of the nurse manager was higher, compared to the perceived perception of these individuals. In addition, a statistically significant difference was observed for area of change and production (P<0.01). In this research, the highest and lowest means of the perceived viewpoint of nurse managers were related to the area of employees (17.20) and task (15.02), respectively. Conclusion: According to the results of this study, there was a difference between nurse managers and nursing personnel in terms of expectations toward nurse managers' leadership styles, which confirms the importance of comparison and evaluation of preferred and perceived leadership styles of nurse managers and staff.