As learner autonomy has increasingly been recognized in language teaching-learning as an ideal educational goal, the existing scholarship on the topic has been focused on teachers and students. Rarely do scholars look at how pre-service teachers, as the future generation of teachers, value autonomy and therefore prepare them to become autonomy-supportive teachers. Against this tendency, this paper argues for the importance of pedagogical investment and initiatives to help pre-service teachers to play an influential role in the establishment of an autonomy-supportive learning environment. It revisits the underpinning theory, concepts, history, and seminal works on LA and TA construct, autonomysupportive pedagogy, and pre-service teacher education initiatives for learner and teacher autonomy. The discussion has provided the rationales why pre-service teachers should be prepared to be teachers having sound TA and supporting to LA, the characteristics of autonomy supportive pedagogy, and some initiatives for learner and teacher autonomy including the principles, instruments, model of intervention, and the grounding theory. Finally, this paper offers a praxeological contribution to the development of EFL practices oriented to democratic and lifelong learning in education. This elaboration might bring some insight for teacher educators and curriculum developers to consider and integrate the value of TA and LA in pre-service teacher education and for autonomy researchers to explore, conceptualize, and design some initiatives for TA and LA workable for pre-service teachers.