2021
DOI: 10.1016/j.media.2021.102169
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Learning to synthesise the ageing brain without longitudinal data

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Cited by 38 publications
(49 citation statements)
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“…In this paper, x is a brain image, y is the AD diagnosis of x, and v represents the target age a and AD diagnosis on which the generator G is conditioned. We use the brain ageing generation model proposed in [28] as G, and a VGG-based [25] AD classification model as C. Note that we only change the target age a in this paper, thus we write the generative process as x = G(x, a) for simplicity.…”
Section: Notations and Problem Overviewmentioning
confidence: 99%
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“…In this paper, x is a brain image, y is the AD diagnosis of x, and v represents the target age a and AD diagnosis on which the generator G is conditioned. We use the brain ageing generation model proposed in [28] as G, and a VGG-based [25] AD classification model as C. Note that we only change the target age a in this paper, thus we write the generative process as x = G(x, a) for simplicity.…”
Section: Notations and Problem Overviewmentioning
confidence: 99%
“…The brain ageing generative model used in this paper is adopted from a recent work [28], which takes a brain image and a target age as inputs and outputs an aged brain image 3 . The original model used ordinal encoding to encode the conditional age and AD diagnosis, where the encoded vectors are discrete in nature, which hinders gradient backpropagation to update these vectors.…”
Section: Fourier Encoding For Conditional Factorsmentioning
confidence: 99%
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“…Recently, GANs have also been applied to longitudinal MR image prediction. For example, Xia et al (2019) proposed a conditional GAN that conditioned on age and health state (status of Alzheimer's Disease) to predict brain aging trajectories. In (Bowles et al, 2018;Ravi et al, 2019), a GAN is used to predict the Alzheimer's related brain degeneration from existing MR images, where biological constraints associated with disease progression are integrated into the framework.…”
Section: Introductionmentioning
confidence: 99%