Left and right ventricular systolic long-axis function and diastolic function in patients with takotsubo cardiomyopathy

Abstract

Takotsubo cardiomyopathy temporarily affects systolic LV and RV function, while most diastolic parameters remain unchanged.

Diastolic function improves after resolution of takotsubo cardiomyopathy

“…These findings differ from the report by Loiske et al, (2011), in that conventional DF parameters were shown to improve over time, corrected or at least uncorrected. Likely, this is secondary to the higher sample size of ours.…”

“…Substandard inclusion might be a contributing factor, for example incomplete (or incorrect) ICD coding regarding the U.S. study part. Although this is in line with many echocardiographic TTC studies, due to its elusive natural course, while we actually obtained results that could not be proven as significant previously (Loiske et al ., ), implying that our cooperation still paid off in this respect. It is important to recall, however, that the population size affects the degree of significance.…”

“…However, in the present study, no statistical differences could be proven for several other diastolic indices (Table ). DT and IVRT were around the upper side of the expected range, consistent with impaired relaxation and age‐appropriate findings (Appleton, ), but this was observed at both phases and is still in line with previous (Loiske et al ., ). Diastolic filling time is influenced by heart rate and R‐R interval (Cui et al ., ).…”

“…In a previous TTC study, it was shown that both LV systolic and diastolic velocities measured by pulsed‐wave Doppler are improved, but other conventional diastolic parameters, often used in clinical echocardiographic practice (e.g. E/A ratio), could not be proven to be statistically changed from acute to recovery phase (Loiske et al ., ). This lack of improvement in conventional diastolic parameters occurred despite finding an improvement in systolic function.…”

Multidisciplinary assessment of tako tsubo cardiomyopathy: a prospective case study

“…However, we took only one blood sample and the routine use of intravenous diazepam before catheterization in our institution might have reduced catecholamine excretion [28]. Furthermore, ejection fractions as measured by echocardiography (recently published in detail elsewhere [29]) and MRi were reduced only moderately compared with findings by others [2,27]. We have no definite explanation to this difference; the timing of examinations in our study was identical to the previous ones and in line with these studies ejection fraction improved to normal.…”