Left Ventricular Noncompaction Combined With Epinephrine-Secreted Pheochromocytoma Inducing Heart Failure

Abstract

SummaryPheochromocytomas and left ventricular noncompaction (LVNC) are both rare diseases. In this patient, the long duration of the catecholamine-secreted pheochromocytoma caused myocardial ischemia, pressure overload, and hypertrophy, resulting in the onset of heart failure (HF). The LVNC might be associated with the acute attack of HF induced by the pheochromocytoma. This is the first case reporting LVNC in combination with HF secondary to pheochromocytoma. (Int Heart J 2016; 57: 254-257)

Cardiomyopathy Phenotypes and Pregnancy Outcomes with Left Ventricular Noncompaction Cardiomyopathy

“…[2][3][4][5] The same is true of women of reproductive age. 6) In recent years, the prognosis of patients with LVNC has improved, as more benign LVNC that has preserved cardiac size and function has been diagnosed and as more cases of LVNC have been identified and treated earlier. 2,3) Notably, more women with LVNC will become pregnant.…”

The Intra-Pericardial Paraganglioma Presenting as Ascites and Hemopericardium with Impending Tamponade

“…Patients with functionally-active tumors present with the signs and symptoms of catecholamine excess, such as hypertension, headaches, sweating or palpitations. 5) In contrast, functionally-inactive tumors present with the symptoms of heart failure or ischemia due to vascular compression and the obstruction of systemic, pulmonary or coronary blood flow. In the literature, about 10% of reported paraganglioma are clinically silent, and 20% of them are nonfunctioning and may present as a mass with symptoms related to compression of other organs, such as chest pain, wheezing, pitting edema, and associated compression signs.…”

Two Patients with Coincident Noncompacted Myocardium and Hypertrophic Cardiomyopathy

“…3) Despite the hypertrophic LVNC, LVNC can also be associated with dilated and restrictive cardiomyopathy, or with congenital heart disease like Ebstein's anomaly, pulmonic stenosis, and pulmonary atresia, or some other diseases. [13][14][15] Heart failure and arrhythmias influence mortality in LVNC, and hybrid subtypes are often accompanied by diastolic dysfunction and hypercontractile systolic dysfunction. 3,10,16) In adults, some hybrid phenotypes seemed to have similar outcomes to LVNC alone, but the progno-sis in neonates or in hypertrophic dilated LVNC phenotype was worse than LVNC alone.…”