1970
DOI: 10.1161/01.res.26.1.71
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Left Ventricular Wall Stress Calculated from One-Plane Cineangiography

Abstract: Left ventricular dimensions from routine clinical one-plane cineangiograms were combined with left ventricular pressure measurements to permit calculation of left ventricular wall stresses. The 25 patients included 12 with normal left ventricular dynamics, 6 with volume overload, 3 with outflow obstruction, and 4 with cardiomyopathy. Average stresses calculated on the basis of an ellipsoid model agreed with average values obtained from the exact solution of a thick-walled elastic ellipsoidal shell. Peak values… Show more

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Cited by 195 publications
(57 citation statements)
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“…One important shortcoming, however, is that we have examined an average wall stress across the entire thickness of the LV wall. More appropriate to the study of mechanisms of hypertrophy would be assessment of a "fiber-corrected stress," such as has been recently described by Falsetti, Mates, Grant, Greene, and Bunnell (32).…”
Section: Resultsmentioning
confidence: 99%
“…One important shortcoming, however, is that we have examined an average wall stress across the entire thickness of the LV wall. More appropriate to the study of mechanisms of hypertrophy would be assessment of a "fiber-corrected stress," such as has been recently described by Falsetti, Mates, Grant, Greene, and Bunnell (32).…”
Section: Resultsmentioning
confidence: 99%
“…Samples were taken from the free wall of the left ventricle, 1 cm above the apex at the anticipated site of venting; these were 6-8 mm long and 1-2 mm in diameter. This was limited to patients with pure mitral stenosis because the left ventricle does not enlarge and frequently exhibits normal function in adults with this disease (33,34 To assess whether the lipid composition of the ventricle was altered in a manner similar to the diabetic animal model (4), 1-g samples of grossly normal ventricle were taken from the same sites as the tissue for morphological examination. After trimming, these were analyzed for triglyceride (35), phospholipid (36), and cholesterol (37).…”
Section: Methodsmentioning
confidence: 99%
“…Several investigators have developed quantitative models which relate the pressure generated in a ventricular chamber to the force generated by its constituent muscle fibers (Falsetti et al, 1970;Anderson et al, 1974; also see Yin, 1981, for a recent review). Most of them can be expressed in the following form:…”
Section: Normalized Responses Of Both the Left (O) And The Right (X) mentioning
confidence: 99%