Background: Uterine leiomyoma is the most common benign neoplasm in women of reproductive age group. Hysterectomy is a mode of therapy
in uterine Leiomyoma. The objective of this study was to evaluate the histopathological changes in hysterectomy specimens with uterine
leiomyomas. This is a retrospective study of one hundred sixty eight patients w Methods: ho underwent hysterectomy for uterine leiomyoma.
Results: Uterine leiomyoma was most common in the age group of 41-50 years (54.76%). Most common location of leiomyoma was intramural
(51.2%). Degenerative changes were seen in 10.72% cases. Hyaline degeneration was the most common type of degenera-tion (7.14%).
Proliferative endometrium was the most common endometrial pattern (63.1%) in uterine leiomyoma. Associated malignant lesions were observed
in 1.8 % cases of uterine leiomyoma. Uterine leiomyoma is associated wi Conclusion: th degenerative changes and coexistent benign and
malignant patholologies. Histopathological examination of hysterectomy specimens should be done to conrm the diagnosis and rule out other
pathologies, especially malignant lesions.