Leiomyosarcoma of the Larynx: A Case Report

Abstract

Leiomyosarcoma of the larynx is an extremely rare neoplasm ; only about 50 cases have been reported in the English-language literature. We report a new case of laryngeal leiomyosarcoma in a 65-year-old man. The metastatic work-up was negative, and thepatient underwent total laryngectomy. He remained disease-free J2 months postoperatively.

Spindle cell lesions of the head and neck: an overview and diagnostic approach

“…It has been described in the sinonasal tract, oral cavity, maxilla, pharynx, larynx and salivary glands, as well as arising in the soft tissues of the neck, [22][23][24][25][26] although all are rare. Histologically, this diagnosis should be suspected in cases composed of spindle cells arranged in a monomorphic pattern with elongated, blunt-ended nuclei at least focally.…”

Leiomyosarcoma of the Larynx: A Complex Diagnosis

“…First-line treatment should be tumor resection with wide margins, reserving radiotherapy as adjuvant treatment or in case of recurrence or persistent tumor. 10,11 Chemotherapy usually is suggested for distant metastases. 12 Even though if LLMS is a very rare laryngeal malignancy, it should be considered when dealing with laryngeal abscess, especially with cartilage involvement.…”

Laryngeal Leiomyosarcoma

“…Primary treatment choice for LLMS is surgery (5). The best prognosis is obtained by completely removing the tumor with wide surgical margins (11,12). In the absence of neck metastasis, neck dissection is not required (6).…”