Leiomyosarcoma of the Right Ovarian Vein: a Case Report with Multimodality Management and Long-Term Follow-Up

Rajpurohit, Virendra; Mehta, Pooja; Kothari, Nirupama; Nathani, Sanjay

doi:10.1007/s13193-019-00936-3

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…Primary RVLMS of the ovarian vein is an unusual condition; only about 23 cases have been recorded [6][7][8][9][10][11][12]. Despite our extensive review of English literature, we could not find any similar case of RVLMS of the gonadal vein in a male patient.…”

Section: Discussionmentioning

confidence: 90%

Primary Leiomyosarcoma of the Ovarian Vein Causing Obstructive Uropathy: A Case Report

Hajji¹,

Azami²,

Adlouni³

et al. 2022

Cureus

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Retroperitoneal vascular leiomyosarcoma (RVLMS) are rare soft-tissue sarcomas that most commonly arise from large blood vessels and have a poor prognosis. We present the case of a 61-year-old woman who presented with isolated left flank pain. Abdominal computed tomography and magnetic resonance imaging revealed a 5 cm retroperitoneal soft-tissue mass that was contiguous with the left ovarian vein and connected to the proximal ureter, causing hydronephrosis. As ureteroscopy suggested extrinsic compression of the ureter, a percutaneous biopsy of the mass was obtained, whereupon diagnosis of leiomyosarcoma was made. Radical en-bloc excision of the tumor, including the involved upper urinary tract and the gonadal vein, was performed. The tumor proved to be a leiomyosarcoma arising from the ovarian vein wall. No adjuvant therapy was planned, and no recurrence was noticed at her 24-month follow-up. Primary RVLMS of the ovarian vein is an uncommon condition. To date, only a few sporadic cases have been reported in the literature. What makes the present case further interesting is the unusual tumor’s relationship with the patient’s ureter, raising both diagnostic and management challenges. To our best knowledge, this is so far the fourth reported case of its kind to cause ureteral obstruction.

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Section: Discussionmentioning

confidence: 90%

Primary Leiomyosarcoma of the Ovarian Vein Causing Obstructive Uropathy: A Case Report

Hajji¹,

Azami²,

Adlouni³

et al. 2022

Cureus

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“…In total, 19 cases of LOV have been reported (Table 1). [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] The ovarian vein extends from the plexus near the ovary and fallopian tube to the renal vein. 23 We assigned the LOV into either the upper or lower regions based on the tumor localization in the ovarian vein above or below the L4 level, given that tumors arising from the lower segment of the ovarian vein are potentially confused with internal reproductive malignancies.…”

Section: Discussionmentioning

confidence: 99%

Leiomyosarcoma arising from the ovarian vein as a gynecologic malignancy: Two case reports and a review of the literature

Yokoyama

Goda

Sato

et al. 2022

J of Obstet and Gynaecol

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Leiomyosarcoma arising from the ovarian vein has rarely been reported. Herein, we report two cases from a single institute. Given their direct connections to ovarian vessels, both leiomyosarcomas were initially suspected to be gynecological malignancies. In one case, leiomyosarcoma was discovered incidentally without any clinical symptoms; it had a close connection with the ovarian vein, was removed surgically, and the patient has survived for over 12 years. In another case, bowel obstruction caused by the tumor helped to identify metastatic leiomyosarcoma. Blood flow was supplied by the ovarian artery and grew into the lumen of the ovarian vein without invading adjacent organs. After surgical resection, the patient underwent 18 months of chemotherapy prior to palliative care. We propose that leiomyosarcoma arising from the ovarian vein should be treated as a gynecologic malignancy, especially if it develops in the lower abdomen.

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Clinical case of long-term treatment of patient with uterine high-grade leiomyosarcoma

Rozonova¹,

Артамонова

Козлов³

2021

Medicinskij alfavit

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Uterine leiomyosarcoma refers to malignant tumors with an aggressive course, poor prognosis, and unsatisfactory long-term treatment results. The five-year overall survival rate ranges from 52–85% for the first stage of the disease to 10–29% for the fourth stage. The treatment method that determines the prognosis of both localized and disseminated leiomyosarcomas is currently radical surgery. In the case of unresectable leiomyosarcomas, drug therapy is performed. The problem of choosing the optimal treatment method for each patient with leiomyosarcoma is still relevant. We present a case of long-term treatment of a patient with high-grade uterine leiomyosarcoma from our own clinical practice. During treatment, the patient underwent 4 surgical interventions and 9 lines of drug therapy. At the moment, the patient is in the process of 10 lines of treatment. Duration of life from the moment of diagnosis is 108 plus months, and from the moment of dissemination of the disease is 97 plus months. This clinical case shows that timely performance of radical surgical interventions and rational choice of drug therapy regimens can significantly increase the average survival rate.

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Leiomyosarcoma of the Right Ovarian Vein: a Case Report with Multimodality Management and Long-Term Follow-Up

Cited by 3 publications

References 12 publications

Primary Leiomyosarcoma of the Ovarian Vein Causing Obstructive Uropathy: A Case Report

Primary Leiomyosarcoma of the Ovarian Vein Causing Obstructive Uropathy: A Case Report

Leiomyosarcoma arising from the ovarian vein as a gynecologic malignancy: Two case reports and a review of the literature

Clinical case of long-term treatment of patient with uterine high-grade leiomyosarcoma

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