Leitlinienreport zur aktualisierten S3-Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV) zur Prävention, Diagnostik und Behandlung von Gallensteinen

Jansen, Petra Lynen; Gutt, Carsten N.; Jenssen, Christian; Barreiros, A. P.; Stokes, Caroline S.; Neubrand, Michael; Lammert, Frank

doi:10.1055/a-0643-4420

Cited by 8 publications

(3 citation statements)

References 847 publications

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“…Как и при ЖКБ, в формировании БС большое значение имеют нарушения питания, экологически неблагоприятные факторы, низкая физическая активность и частые психоэмоциональные перегрузки. Факторы риска формирования БС [3,8] представлены в табл. 2.…”

Section: факторы риска и особенности патогенеза бсunclassified

Biliary sludge: pathogenesis, etiology and drug therapy

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Авалуева

Serkova

et al. 2021

Terapevticheskii arkhiv

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Aim. To evaluate the effectiveness of the use of ursodeoxycholic acid (UDCA) for the treatment of biliary sludge (BS) and to compare the therapeutic effectiveness of the German substance UDCA and generic drugs from other manufacturers. Materials and methods. The study involved 65 patients diagnosed with BS (K80.8). To assess the severity of BS, ultrasound of the gallbladder was performed before treatment, after 1, 3, 6 months during therapy, as well as an assessment of its contractility. All patients were randomized into 2 groups. Patients of the main group received UDCA Ursofalk (Germany) at a dose of 10 mg/kg for at least 6 months. Patients in the comparison group received UDCA (another manufacturer) at a dose of 10 mg/kg for at least 6 months. Results. After 3 months of follow-up, the number of patients with dissolved sludge in the main group was 87.1%, while in the comparison group 50%. In 71% of patients, the normalization of the lean volume of the gallbladder was noted, and in the comparison group only in 47.1%. After 6 months of follow-up, complete resolution of BS in the main group was observed in 93.5% of cases, and in the comparison group in 73.6% of cases. Conclusion. As a result of the study, the high effectiveness of Ursofalk during oral litolysis in patients with stage I GI (BS) in the first 3 months of therapy, as well as the normalization of the contractile function of the gallbladder, were noted.

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Section: факторы риска и особенности патогенеза бсunclassified

Biliary sludge: pathogenesis, etiology and drug therapy

Бакулин

Авалуева

Serkova

et al. 2021

Terapevticheskii arkhiv

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“…In den aktuell gültigen IMPP-Gegenstandskatalog (GK2) wurden erstmalig im Jahr 2019 explizit Lernziele zu Leitlinien aufgenommen. Die Kennzeichnung von studierendengerechten Leitlinieninhalten bei der Aktualisierung der Gallensteinleitlinie (Lynen Jansen et al 2018) zeigt konkrete Umsetzungsmöglichkeiten auf und kann als Orientierung dienen, wie für Studierende relevante Inhalte in Leitlinien künftig gekennzeichnet werden können. In der Lehre haben sich von ersten Pilotierungen der Vermittlung von Leitlinien in der Allgemeinmedizinischen Lehre bis hin zu internationalen Curricula zu Clinical Reasoning in den letzten 15 Jahren enorme Entwicklungen aufgetan.…”

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“…In the currently valid IMPP subject catalogue (GK2), learning objectives on guidelines were explicitly included for the first time in 2019. The labelling of guideline content suitable for students in the update of the gallstone guideline (Lynen Jansen et al 2018) shows concrete implementation possibilities and can serve as an orientation for how content relevant for students can be labelled in guidelines in the future. In teaching, enormous developments have taken place over the last 15 years.…”

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confidence: 99%