Lentinus edodes heterogalactan: Antinociceptive and anti-inflammatory effects

Structural Features and Healthy Properties of Polysaccharides Occurring in Mushrooms

“…Besides lentinan, which is a (1→3),(1→6)-linked D-polysaccharide [60], a heteropolysaccharide consisting of a fucomannogalactan with a main chain of (1→6)-linked α-D-galactopyranosyl units branched at O-2 has been extracted [61], as well as a glucogalactan bound by (1→3),(1→4) linkages [62].…”

Studies on antioxidative and immunostimulating fucogalactan of the edible mushroom Macrolepiota dolichaula

“…[1][2][3] Some heterogalactans with (1→6)-linked α-D-Galp backbone terminated by fucose or mannose have been isolated from mushrooms and reported. [4][5][6] A few fucogalactans 7,8 and manogalactan 9 are reported to exhibit promising antitumor and antiinflammatory activities.…”

Effect of Sulfated Modification on the Molecular Characteristics and Biological Activities of Polysaccharides fromHypsizigus marmoreus

“…[4][5][6] The polysaccharides have therefore been isolated from various mushrooms and their biological activities have been reported. [7][8][9] A treatment with soluble polysaccharides extracted from Lyophyllum decastes Sing increased the number of peritoneal macrophages in mice and inhibited the growth of tumor cells, possibly through enhancement of the host defense mechanism. 10) In contrast, Lavi et al 9) have reported that treating with an aqueous polysaccharide from Pleurotus ostreatus exhibited direct cytotoxic activity toward the HT-29 colon cancer cell line by up-regulating the pro-apoptotic molecules, Bax and cytosolic cytochrome-c.…”