Lepidium meyenii (Maca) reversed the lead acetate induced—Damage on reproductive function in male rats

Rubio, Julio; Riqueros, M.; Gasco, Manuel; Yucra, Sandra; Miranda, Sara; Gonzales, Gustavo F.

doi:10.1016/j.fct.2006.01.007

Cited by 90 publications

(73 citation statements)

References 53 publications

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“…En un posterior estudio se observó que los niveles de testosterona intratesticular y los niveles séricos de testosterona fueron similares en el grupo que recibió maca negra por 7 días que en el grupo control (48) . Se han evaluado también los niveles de testosterona en otras situaciones, una evaluó el efecto de la administración del acetato de plomo (49) y otro para evaluar el efecto de la altura (50) . La maca no revirtió el efecto deletéreo del plomo sobre los niveles de testosterona sérica (49) .…”

Section: Maca Y Hormonas Sexualesunclassified

“…Se han evaluado también los niveles de testosterona en otras situaciones, una evaluó el efecto de la administración del acetato de plomo (49) y otro para evaluar el efecto de la altura (50) . La maca no revirtió el efecto deletéreo del plomo sobre los niveles de testosterona sérica (49) . En la altura se observa un mayor valor de testosterona en el grupo tratado con maca con respecto al control sin maca; a los 14 y 21 días de exposición a la altura los valores de testosterona sérica son similares entre el control y el grupo tratado con maca (50) .…”

Section: Maca Y Hormonas Sexualesunclassified

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Maca (Lepidium meyenii WALP), una revisión sobre sus propiedades biológicas

Gonzáles

Villaorduña

Gasco

et al. 2014

Rev Peru Med Exp Salud Publica

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RESUMENLa maca (Lepidium meyenii) es una planta que crece sobre los 4000 metros de altitud en los Andes Centrales del Perú, presenta diferentes variedades de acuerdo al color de su hipocótilo. La presente revisión resume los resultados de estudios sobre los efectos de la maca en la función sexual, la espermatogénesis, la función reproductiva femenina, la memoria, la depresión y la ansiedad, como energizante y contra la hiperplasia benigna de próstata, osteoporosis y síndrome metabólico. Se discute también su efecto antienvejecimiento y la seguridad en su consumo. Se han demostrado diferencias en el efecto de las variedades negra, amarilla y roja de maca. La maca negra es la que mejores resultados presenta sobre la espermatogénesis, la memoria y contra la fatiga, mientras que la maca roja es la variedad que mejor revierte la hiperplasia benigna de próstata y la osteoporosis inducida experimentalmente. Además, la maca reduce los niveles de glucosa, y su consumo se relaciona con la reducción de la presión arterial y un mejor puntaje de salud. Estudios experimentales han demostrado que el consumo a corto como a largo plazo no muestra toxicidad tanto in vivo como in vitro. A pesar que los estudios experimentales han demostrado que la maca presenta diversos efectos benéficos, son necesarios más estudios clínicos para confirmar estos resultados. Palabras clave: Espermatogénesis; Hiperplasia benigna prostática; Osteoporosis; Fatiga; Toxicidad (fuente: DeCS BIREME). MACA (Lepidium meyenii Walp), A REVIEW OF ITS BIOLOGICAL PROPERTIES ABSTRACTMaca (Lepidium meyenii) is a plant that grows above 4000 altitude meters in Peru's Central Andes; it has different varieties according to the color of the hypocotyl. This review summarizes the results of studies about the effects of maca on sexual function, spermatogenesis, female reproductive function, memory, depression and anxiety, and energy as well as effects on benign prostatic hyperplasia, osteoporosis and metabolic syndrome. Its anti-aging effect is also discussed as well as safety in consumption. Differences have been shown between the effects of the black, yellow and red maca varieties. Black maca shows the best results on spermatogenesis, memory and fatigue, while red maca is the variety that reverses the benign prostatic hyperplasia and experimentally induced osteoporosis. In addition, maca reduces the glucose levels, and its consumption is related to the lowering of blood pressure and an improved health score. Experimental studies have proven that short and long term consumption don't show in vivo and in vitro toxicity. Although experimental studies have shown that maca has diverse beneficial effects, more clinical studies are needed to confirm these results.

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Section: Maca Y Hormonas Sexualesunclassified

Maca (Lepidium meyenii WALP), una revisión sobre sus propiedades biológicas

Gonzáles

Villaorduña

Gasco

et al. 2014

Rev Peru Med Exp Salud Publica

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“…In 2001, maca was reported to increase sperm count in men [20]. Sperm Count: Scientific studies have shown that maca may increase daily sperm production (DSP), epididymal sperm count or vas deferens sperm count in both healthy rats [20,21] or when spermatogenesis was disturbed by different experimentally-induced abnormal conditions such as exposure to high altitude [22], injection of malathion [23], or administration of lead acetate [24].…”

Section: Male Reproductionmentioning

confidence: 99%

Lepidium meyenii(Maca): A Plant from the Highlands of Peru – from Tradition to Science

Gonzáles

Gonzales

Gonzales-Castañeda

2009

Forsch Komplementmed

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This review summarizes the current state of knowledge on Lepidium meyenii (maca), a cruciferous plant (Brassicaceae family) which is cultivated exclusively at an altitude of 4,000–4,500 m in the Peruvian Central Andes. Maca is traditionally used for its nutritional and presumed medici-nal properties. Over the past 20 years, interest in maca has increased in many parts of the world, and since 2005 maca is considered one of the seven Peruvian flag products. Maca is exported as powder, capsules, pills, flour, liquor, and extracts. There are different types of maca with differ-ent colors ranging from white to black. We have studied the pharmacological effects of 3 types; yellow, black, and red maca. Evidence from experimental studies indicates effects of maca on nutrition, fertility, memory, and mood. Black maca has better effects on sperm production than yellow maca which has only moderate effects. Red maca, however, has no effect on sperm production. However, red maca has been shown to reduce prostate size in rats in which prostate hyperplasia had been induced with testosterone enanthate; yellow maca has shown moderate effects here, whereas black maca has not shown any effects. Randomized clinical trials have shown that maca has favorable effects on energy and mood, may decrease anxiety and improve sexual desire. Maca has also been shown to improve sperm production, sperm motility, and semen volume. Serum levels of testosterone, estradiol, LH, FSH, and prolactin were not affected. The exact mechanisms of action are still unclear, but so far research clearly indicates that various bioactive constituents contribute to the clini-cal effects reported.

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“…Thus, black maca appeared to have more beneficial effect on sperm counts and epididymal sperm motility than red and yellow maca. 12 In a similar study, Rubio et al 10 determined that maca reduced the harmful effect on daily sperm production caused by lead acetate treatment. Consequently, maca may become a potential treatment of male infertility associated with lead exposure.…”

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confidence: 86%