Les affections rhumatologiques inflammatoires ayant motivé une hospitalisation au centre hospitalo-universitaire de Cocody (Abidjan) entre mars 1998 et mars 2000

Daboiko, J. C.; Eti, E.; Yapi, Ignace Dollo; Ouali, Boubacar; Ouattara, B.; N'zue, M. Kouakou

doi:10.1016/j.rhum.2004.04.014

Cited by 4 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This frequency is higher than those found in Europe [17], North Africa [18] and United States [19]. In sub-Saharan Africa, Teclessou et al [20] and Daboiko et al [21] reported death rates of 22.5% and 22.4% respectively. These results demonstrate the still high mortality associated with SLE in our black African countries.…”

Section: Discussionmentioning

confidence: 75%

Clinical Presentation and Evolution of Systemic Lupus at the CNHU-HKM of Cotonou (Benin)

Anthelme,

Armand,

Abdul-Farid

et al. 2023

OJIM

View full text Add to dashboard Cite

Introduction: Systemic lupus erythematosus (SLE) is a non-organ-specific autoimmune disease with an unknown origin. The unchanged trend of premature mortality in systemic lupus erythematosus shows the critical unmet need for improved and optimized management of systemic lupus erythematosus. Objectives: To analyze the clinical features and the prognostic factors of death in SLE at the CNHU-HKM of Cotonou. Patients and Methods: This was a retrospective cohort study. It was conducted over the period from January 1st 2010 to December 31st 2021. The study population consisted of all patients followed for SLE in the internal medicine, rheumatology, nephrology and dermatology wards at the CNHU-HKM of Cotonou. Results: 88 cases were recorded in 12 years, i.e. an incidence of 7 cases per year. There were 80 women and 8 men with a mean age of 36.4 ± 13.1 years. The clinical picture was dominated by mucocutaneous (86.3%) and osteoarticular (71.5%) disorders. The biological abnormalities observed were anemia (78.8%), lymphopenia (43.1%) and thrombocytopenia (17.7%). 39 patients had renal damage (44.3%). The incidence of death was 17%. Factors associated with death were renal involvement, infectious complications, high initial SLEDAI score, flare, thrombocytopenia and lymphopenia. Conclusion: Mortality related to SLE remains high at the CNHU-HKM of Cotonou. Renal involvement, infectious complications, high initial SLEDAI score, flare, lymphopenia and thrombocytopenia were the factors associated with death. The presence of these factors should lead to an evaluation of the treatment.

show abstract

Section: Discussionmentioning

confidence: 75%

Clinical Presentation and Evolution of Systemic Lupus at the CNHU-HKM of Cotonou (Benin)

Anthelme,

Armand,

Abdul-Farid

et al. 2023

OJIM

View full text Add to dashboard Cite

show abstract

“…This manifestation is at the forefront of the disease and is often part of the initial presentation in Caucasian patients as well as in other series reported in India [26][27][28], Saudi Arabia and China with more than 80% of patients having Raynaud's phenomenon [29][30][31]. Raynaud's phenomenon appears to be rare in the MCTD of black African subjects [10][11][12]. There were only two cases of Raynaud's phenomenon among the 10 patients in the series from Gabon and Senegal [10,11].…”

Section: Discussionmentioning

confidence: 99%

“…In populations of African ancestry, the clinical presentation and epidemiology of systemic auto-immune diseases, particularly connective tissue disease are not always similar to data from Caucasian or Asian populations [6][7][8][9]. The epidemiology and clinical features of MCTD and OAS in populations of African ancestry have not been well described heretofore, except in small series of adults from Gabon, Senegal and Ivory Coast [10][11][12]. There has never been a specific description in children of this ethnic group of African ancestry or in Afro-Caribbean population.…”

Section: Introductionmentioning

confidence: 99%

Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

Felix,

Osei,

Delion

et al. 2024

Pediatr Rheumatol

View full text Add to dashboard Cite

Introduction Overlap autoimmune syndromes (OAS) and mixed connective tissue disease (MCTD) are rare in children. We performed a retrospective, longitudinal and descriptive study of Afro-Caribbean patients from the French West Indies followed for MCTD and OAS to describe their characteristics and outcomes during childhood. Methods Retrospective study from January 2000 to 2023. Listings of patients were obtained from multiple sources: computerized hospital archives and national hospital-based surveillance system, registry of pediatricians and adult specialists in internal medicine and the national registry for rare diseases. MCTD was defined according to Kasukawa’s criteria. OAS was defined as overlapping features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and dermatomyositis/autoimmune myositis (DM/AM). Results Sixteen patients were included over a 23-year period (10 MCTD and 6 OAS). The incidence was 0.23 per 100,000 children-years. The mean age at diagnosis was 11.9 years old (2.4–17) with median follow up of 7.9 years (2.1–19.6). SLE phenotype was present in the highest, followed by SSc and DM/AM. Patients had an average of three flares during childhood (1–7). A quarter (25%) had symptomatic pulmonary arterial hypertension (PAH). Ninety-four percent received steroids during follow-up and 88% required a corticosteroid-sparing therapy. Three patients (19%) developed SLE after more than 10y of follow-up. There were no death and no chronic organ failure. Conclusion This is the largest pediatric cohort of MCTD and OAS in Afro-descendant patients treated in a country with a high standard of care. The clinical evolution did not differ between MCTD and OAS. The main complication was PAH, more frequent in our cohort.

show abstract

“…Dans la série Camerounaise de 36 rhumatismes inflammatoires chroniques, Noche CD a recensé 2 cas de CM entre 2004 et 2012 alors que la polyarthrite rhumatoïde et le lupus systémique représentaient 16 et 8 cas respectivement [ 20 ]. Daboiko et al ont retrouvé 2 cas de CM parmi 18 cas de connectivites dominés par le LES (10 cas) entre 1998 et 2000 en Côte d'Ivoire [ 21 ]. Lutalo SK rapporte aussi 2 cas au Zimbabwe en 1985 avec plutôt un profil d'overlap syndrome [ 22 ].…”

Section: Discussionunclassified

La connectivite mixte: prévalence et caractéristiques cliniques chez le noir africain, étude de 7 cas au Gabon et revue de la littérature

Missounga¹,

Ba²,

Ondo³

et al. 2017

Pan Afr Med J

View full text Add to dashboard Cite

La littérature rapporte que la connectivite mixte semble plus fréquente dans la population noire et chez les asiatiques. Le but de l'étude était de déterminer la prévalence de la connectivite mixte (CM) parmi les connectivites et l'ensemble des pathologies rhumatologiques dans une population hospitalière au Gabon; de décrire ensuite les caractéristiques cliniques de la maladie. Il s'agissait d'une étude rétrospective des dossiers de patients suivis pour connectivite mixte (critères de Kasukawa) et les autres entités de connectivites (critères ACR) en rhumatologie au CHU de Libreville entre janvier 2010 et décembre 2015. Pour chaque cas de CM, les manifestations articulaires et extra-articulaires, le taux d'anticorps anti-U1RNP, l'évolution, étaient les paramètres étudiés. Sept cas ont été colligés en 6 ans parmi 6050 patients et 67 cas de connectivites soit une prévalence de 0,11% et de 10,44% respectivement. Il s'agissait de 7 femmes (100%), d'âge moyen de 39,5 ans. Les signes articulaires comprenaient: polyarthrite, myalgies, doits boudinés et phénomène de Raynaud dans 87,5%, 87,5%, 28,6% et 14% respectivement. Les 7 patients avaient un taux d'anti-U1RNP élevé entre 5 et 35N (N≤7 UI). Un cas de décès par HTAP était constaté. Il s'agit de la série de CM la plus importante rapportée en Afrique noire. La maladie semble rare chez le noir africain, la raison pourrait être génétique. Les aspects démographiques et cliniques paraissent similaires chez les caucasiens, les asiatiques et les noirs hormis une faible fréquence du phénomène de Raynaud chez les noirs.

show abstract

Les affections rhumatologiques inflammatoires ayant motivé une hospitalisation au centre hospitalo-universitaire de Cocody (Abidjan) entre mars 1998 et mars 2000

Cited by 4 publications

References 2 publications

Clinical Presentation and Evolution of Systemic Lupus at the CNHU-HKM of Cotonou (Benin)

Clinical Presentation and Evolution of Systemic Lupus at the CNHU-HKM of Cotonou (Benin)

Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

La connectivite mixte: prévalence et caractéristiques cliniques chez le noir africain, étude de 7 cas au Gabon et revue de la littérature

Contact Info

Product

Resources

About