Les issues des retraitements de la tuberculose dans le service de pneumophtisiologie du CHU d’Antananarivo

Ravahatra, K.; Rakotomizao, Jocelyn Robert; Rakotoson, J.L.; Tiaray, Harison Michel

doi:10.1016/j.rmr.2013.10.362

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Across our entire cohort, favourable treatment outcome was achieved in 31 patients (38%), 24 patients who completed treatment (29%) and 7 patients reported cured (9%). Ravahatra [12] reported a rate of 35.84% of favourable outcome. Nevertheless, these rates are much lower than those reported by Saha [13] (75.2%) in India and by Agodokpessi [14] (80%) in Benin.…”

Section: Resultsmentioning

confidence: 97%

See 1 more Smart Citation

Tuberculosis Re-Treatment Cases and Factors Associated with Unfavourable Outcome at the Fann University Hospital of Dakar, Senegal between 2011 and 2016: A Follow-Up Study

Cissé¹,

Fortes²,

AminataMassaly³

et al. 2019

J Infect Dis Epidemiol

View full text Add to dashboard Cite

Introduction: The aim of our study was to describe the socio-demographic, clinical, therapeutic and evolutionary characteristics of patients admitted to tuberculosis re-treatment and managed at the The Infectious and Tropical Diseases Department (SMIT) screening and tuberculosis treatment center (TTC), to determine the factors associated with unfavourable outcome Methodology: This is a descriptive and analytical retrospective cross sectional study covering all tuberculosis re-treatment cases monitored in the service of infectious and tropical diseases in Fann from 1 January 2011 to 31 December 2016. The Epi-Info software version 7 CDC and SAS (version 9.3, Cary, NC, USA) were used for data entry and analysis. Results: We collected 83 patients as re-treatment tuberculosis cases during the study period, for an annual average of 14 cases. The average age of the patients was 42.2 years ± 13.6 years, with extremes of 16 and 77 years. There was a male predominance (66.3%) with a sex ratio of 1.96. The majority (95.2%) of our patients came from the Dakar region, 42.2% of them from the suburban area. More than two thirds (77.1%) of our patients were hospitalized. Clinically, the average weight at initiation of tuberculosis treatment was 48.1 kg ± 9.9 kg. The isolated pulmonary form accounted for 63%, followed by the multifocal form 23%. HIV seroprevalence was 73.6% and 92.9% of these patients were on cotrimoxazole chemoprophylaxis and 60.7% on ARV treatment. Relapses (61.4%) and treatment after default (36.1%) constituted the majority of the re-treatment circumstances. The unfavourable outcome was related to provenance in suburban areas and outside Dakar (AOR = 17.5; 95% CI: 3.61-85.4). Conclusion: Compliance and monitoring of retreatment cases is important to avoid TB drug resistance. It is necessary to improve the referral and counter-referral system as well as communication between the different tuberculosis treatment centers.

show abstract

Section: Resultsmentioning

confidence: 97%

“…The lethality rate was 25%. In two studies conducted respectively in Benin [10] and Madagascar [12] this lethality was 7% and 5.66%. This high lethality in our series could be related to the fact that 77.1% of our patients were hospitalized, 73.6% were co-infected with…”

Section: Resultsmentioning

confidence: 99%