LES of non-Newtonian physiological blood flow in a model of arterial stenosis

Molla, Md. Mamun; Paul, Manosh C.

doi:10.1016/j.medengphy.2011.11.013

Cited by 99 publications

(70 citation statements)

References 28 publications

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“…They [19][20][21] also have studied the physiological pulsatile flows in a channel with a single stenosis for the Newtonian and non-Newtonian fluids using the large-eddy simulation technique. Again, rheological properties of blood have been studied for transition-to-turbulent condition using LES technique in [22].…”

Section: Introductionmentioning

confidence: 99%

Rheological Behavior of Physiological Pulsatile Flow through a Model Arterial Stenosis with Moving Wall

2015

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The paper presents a numerical investigation of non-Newtonian modeling effects on unsteady periodic flows in a two-dimensional (2D) constricted channel with moving wall using finite volume method. The governing Navier-Stokes equations have been modified using the Cartesian curvilinear coordinates to handle complex geometries, such as, arterial stenosis. The physiological pulsatile flow has been used at the inlet position as an inlet velocity. The flow is characterized by the Reynolds numbers 300, 500, and 750 that are appropriate for large arteries. The investigations have been carried out to characterize four different non-Newtonian constitutive equations of blood, namely, the (i) Carreau, (ii) Cross, (iii) Modified-Casson, and (iv) Quemada. In these four models, blood viscosity is a nonlinear function of shear rates. The Newtonian model has been investigated to study the physics of fluid and the results are compared with the non-Newtonian viscosity models. The numerical results are presented in terms of streamwise velocity, wall shear stress, pressure distribution as well as the vorticity, streamlines, and vector plots indicating recirculation zones at the poststenotic region. Comparison has also been illustrated in terms of wall pressure and wall shear stress for the Cross model considering different amplitudes of wall oscillation.

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Section: Introductionmentioning

confidence: 99%

Rheological Behavior of Physiological Pulsatile Flow through a Model Arterial Stenosis with Moving Wall

2015

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“…However, this method has already been used for modeling of non-Newtonian blood flows through blood vessels (Molla and Paul, 2009). …”

Section: Large Eddy Simulations (Les)mentioning

confidence: 99%

A New Method for Assessing Haemolysis in a Rotary Blood Pump Using Large Eddy Simulations (LES)

Szwast

Moskal

Piątkiewicz

2017

Chemical and Process Engineering

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The opportunity to assess haemolysis in a designed artificial heart seems to be one of the most important stages in construction. We propose a new method for assessing haemolysis level in a rotary blood pump. This method is based on CFD calculations using large eddy simulations (LES). This paper presents an approach to haemolysis estimation and shows examples of numerical simulation. Our method does not determine the value of haemolysis but allows for comparison of haemolysis levels between different artificial heart constructions.

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“…A large number of studies computational [22][23][24][25][26][27] of the hemodynamics in diseased arteries exhibit disordered and turbulent flows in such vessels. Turbulence can significantly affect the pressure and shear stress downstream of the stenosis [28].…”

Section: Computational Fluid Dynamicsmentioning

confidence: 99%

Clinical important hemodynamic characteristics for serial stenosed coronary artery

Bernad¹,

Bernad²,

Totorean³

et al. 2015

Int. J. DNE

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Effects of serial stenosis on coronary hemodynamics are investigated in the human right coronary artery (RCA) by blood flow analysis. The 3D reconstruction of the geometry of the stenosed coronary artery uses the multislice computerized tomography serial images method. Results of the numerical analysis present the hemodynamic characteristics of the serial stenosed coronary artery throughout the flow separation, pressure drop and wall shear stress. The pressure loss associated with recirculation region created in the vicinity of each constriction was found to be large. In two stenoses the corresponding pressure gradients are around 30 mmHg and correspond to the stenosis with fractional flow reserve-FFR < 0.7 (value associated to the severe stenosis). Distal to the stenosis, flow is associated with fluctuations in the wall shear stress and vorticity. Both FFR and CFD analysis help identify intermediate lesions that require intervention and reduce unnecessary procedures with potential complications.

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LES of non-Newtonian physiological blood flow in a model of arterial stenosis

Cited by 99 publications

References 28 publications

Rheological Behavior of Physiological Pulsatile Flow through a Model Arterial Stenosis with Moving Wall

Rheological Behavior of Physiological Pulsatile Flow through a Model Arterial Stenosis with Moving Wall

A New Method for Assessing Haemolysis in a Rotary Blood Pump Using Large Eddy Simulations (LES)

Clinical important hemodynamic characteristics for serial stenosed coronary artery

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