Les tumeurs amyloïdes à localisation trachéo-bronchique exclusive

The characteristics of peripheral lung tumours that suggest their bronchiolo-alveolar origin

“…They concluded that these tumours could be classified histologically under four headings: anaplastic small cell carcinoma; squamous cell carcinoma; anaplastic large cell carcinoma and adenocarcinoma. This classification is not new and is very similar to that used by other workers (Fischer, 1949;McDonald, McBurney, Carlisle and Patton, 1951;Walter and Pryce, 1955; Whitwell, 1961;Delarue, Abelanet and Paillas, 1964), but the recent work has provided a new histogenetic basis for the classification, which suggests that among the tumours of the lower respiratory tract, a distinction should be made between the true bronchogenic carcinomas, which include anaplastic small cell carcinoma and squamous cell carcinoma, and the bronchiolo-alveolar carcinomas which include anaplastic large cell carcinoma and adenocarcinoma, the latter being tumours of the lung parenchyma.On the other hand, bronchial epithelium is, in the main, a lining epithelium and its histological and ultrastructural appearances are different from bronchiolar and alveolar epithelium (Krahl, 1963;Collet, 1965). The latter are directly concerned with respiratory function and are responsible for the growth and regeneration of pulmonary tissue, both in foetal and post-natal life (Willson, 1928;Amprino, 1937;Dunnill, 1962).…”

“…They concluded that these tumours could be classified histologically under four headings: anaplastic small cell carcinoma; squamous cell carcinoma; anaplastic large cell carcinoma and adenocarcinoma. This classification is not new and is very similar to that used by other workers (Fischer, 1949;McDonald, McBurney, Carlisle and Patton, 1951;Walter and Pryce, 1955; Whitwell, 1961;Delarue, Abelanet and Paillas, 1964), but the recent work has provided a new histogenetic basis for the classification, which suggests that among the tumours of the lower respiratory tract, a distinction should be made between the true bronchogenic carcinomas, which include anaplastic small cell carcinoma and squamous cell carcinoma, and the bronchiolo-alveolar carcinomas which include anaplastic large cell carcinoma and adenocarcinoma, the latter being tumours of the lung parenchyma.…”