“…Splenectomy increased the toxicity of p32 and Sr 8 9, but not of AU198• The mortality produced by simultaneous ad ministration of both AU198 and p32 was also not affected by splenectomy, since AU198 effectively eliminates the spleen as a potential protective mecha nism. Harel (84) Littman et al (87). Doses above 5000 rep to the wall of the stomach were found to be lethal.…”