Letter to the editor in response to COVID-19 presenting as acute pancreatitis

Prevalence, Risk Factors, and Outcomes of Hospitalized Patients With Coronavirus Disease 2019 Presenting as Acute Pancreatitis

“…These findings support the notion that pancreatitis should be included in the list of GI manifestations of COVID-19. Although this was speculated previously based on multiple case reports, [2][3][4] it has not been shown until now, to our knowledge, given the overall low prevalence of pancreatitis compared to other GI manifestations. Greater attention should be paid to the history or complaint of abdominal pain, and obtaining serum lipase levels in these patients should be considered.…”

“…2 Alcohol-induced pancreatitis was defined as pancreatitis developing in the setting of alcohol intake with a history of heavy alcohol consumption. 2,3 Gallstone pancreatitis was defined as pancreatitis occurring with imaging showing gallstones/sludge or common bile duct stones/sludge. 2 Drug-induced pancreatitis was defined as pancreatitis occurring in the setting of using one of the medications for which a definite or probable association with acute pancreatitis has been reported in the absence of alcohol use or suspected gallstone etiology.…”

“…1 Some case reports have shown acute pancreatitis as the initial presentation in patients with COVID-19. [2][3][4] As islet cells of the pancreas contain ACE2 receptor proteins, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can bind to these receptors and cause pancreatic injury. 5 Our study aimed to report the point prevalence, risk factors, and outcomes of hospitalized patients with COVID-19 presenting with acute pancreatitis in a large health system and to compare outcomes of pancreatitis in patients without COVID-19.…”

Association between acute pancreatitis and COVID-19 infection: What do we know?

“…Therefore, there is strong evidence for an association between AP and COVID-19, but the diagnosis of COVID-19-related AP is challenging, because other potential etiological factors must be ruled out[ 33 ]. It is important to pay attention to the association between COVID-19 infection and AP[ 11 ]. All known etiological factors, including drugs used in COVID-19 disease, should be ruled out to recognize AP secondary to COVID-19.…”

COVID 19 Pnömonisi Olan Bir Hastada Olası Akut Pankreatit

“…COVID-19 hastalarının bazılarında pankreas enzim yüksekliği ve nadir de olsa AP gelişebilmektedir. AP özellikle ciddi hastalık tablosu ile ilişkilidir (5)(6)(7)(8)(9). Önceki yıllarda yapılan çalışmalarda; viral pankreatitin, Kabakulak, Kızamık, Coxsackie virus, Epstein-Barr virus ve Hepatit-A virüs enfeksiyonuna bağlı gelişebileceği bildirilmiştir.…”