Leucine-coated cobalt ferrite nanoparticles: Synthesis, characterization and potential biomedical applications for drug delivery

Zhang, Hui; Wang, Jianchao; Zeng, Yingzhe; Wang, Guangshuo; Han, Shuai; Yang, Zhitang; Li, Baowei; Wang, Xiaomin; Gao, Jie; Zheng, Lei; Liu, Xiaoyan; Huo, Zhongchao; Yu, Rongmin

doi:10.1016/j.physleta.2020.126600

Cited by 39 publications

(13 citation statements)

References 26 publications

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“…The presence of FeO nanoparticles can also be detected where there is an absorption band around the wavenumber of 500 cm -1 [17]. Figure 3 also shows the absorption band at wavenumber 1218 cm -1 which is the stretching vibration of the M -O -C group [18], the absorption band at wavenumber 1635 cm -1 which is a strain vibration C = O [19], the absorption band at a wavenumber of about 3400 cm -1 caused by the stretching vibration of the O -H bond, and the absorption band observed at about 3600 cm -1 caused by the stretching of the free O -H hydroxyl group [20]. Figure 3 also shows that the intensity of the absorption band at an annealing temperature of 600C has a higher intensity than the other annealing temperatures.…”

Section: Vibration Of Ni04zn05co01fe2o4 Nanoparticlementioning

confidence: 91%

Study of Phase Transformation, Structures, Morphology, and Vibration of Ni-Zn-Co Ferrites Nanoparticles due to Annealing Temperature

Zuhroh

Hidayah

Aturroifah

et al. 2022

J. Phys.: Conf. Ser.

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The good physical and chemical properties of metal ferrite nanoparticles can be used as potential materials when applied. This study aims to explore the physical and chemical properties, such as phase, structure, morphology, and vibration of Ni-Zn-Co ferrites nanoparticles annealed at different temperatures. Ni0.4Zn0.5Co0.1Fe2O4 nanoparticles were synthesized by coprecipitation method and characterized by X-Ray Diffraction (XRD), Transmission Electron Microscopy (TEM), and Fourier Transform Infrared (FTIR) Spectroscopy to determine their structure, morphology, and vibration. Overall, all samples showed spinel cubic structures. In addition, XRD analysis showed the phase transformation from magnetite to hematite by increasing the temperature. The increase of annealing temperature leads to the larger average size of nanoparticles which were estimated by analyzing TEM images. The average diameter of nanoparticles with annealing temperature of 600°C was (10.9 + 0.5) nm and the average diameter of nanoparticles with annealing temperature of 1000°C was (18.6 + 4) nm. FTIR measurements between (4000 – 400) cm-1 confirmed the absorption band in the spectrum. The FTIR spectra of the nanoparticles confirmed the presence of metal ion vibrational bands located at octahedral and tetrahedral sites in 418 cm-1 to 696 cm-1. This implies that Ni-Zn-Co ferrites has truly the spinel cubic structures considering their absorption characteristics at about (500 – 600) cm-1.

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Section: Vibration Of Ni04zn05co01fe2o4 Nanoparticlementioning

confidence: 91%

Study of Phase Transformation, Structures, Morphology, and Vibration of Ni-Zn-Co Ferrites Nanoparticles due to Annealing Temperature

Zuhroh

Hidayah

Aturroifah

et al. 2022

J. Phys.: Conf. Ser.

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“…With this targeted approach, the heating of cancer cells can be attained without damaging surrounding normal tissue, thus increasing the effectiveness and safety of hyperthermia. In a recent report, hyperthermia therapy was employed through utilising cobalt ferrite NPs where 90% doxorubicin delivery was achieved in 6 h at 44 °C [ 54 ]. Nanotherm ® is an FDA-approved formulation comprising iron oxide NPs coated with aminosilanes ( Table 1 ) [ 55 ] and is indicated for hyperthermia treatment of the malignant glioblastoma multiforme [ 56 , 57 ].…”

Section: Iron Oxide Nanoparticles In Cancer Diagnostics and Therapymentioning

confidence: 99%

Advances in the Synthesis and Application of Magnetic Ferrite Nanoparticles for Cancer Therapy

et al. 2022

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Cancer is among the leading causes of mortality globally, with nearly 10 million deaths in 2020. The emergence of nanotechnology has revolutionised treatment strategies in medicine, with rigorous research focusing on designing multi-functional nanoparticles (NPs) that are biocompatible, non-toxic, and target-specific. Iron-oxide-based NPs have been successfully employed in theranostics as imaging agents and drug delivery vehicles for anti-cancer treatment. Substituted iron-oxides (MFe2O4) have emerged as potential nanocarriers due to their unique and attractive properties such as size and magnetic tunability, ease of synthesis, and manipulatable properties. Current research explores their potential use in hyperthermia and as drug delivery vehicles for cancer therapy. Significantly, there are considerations in applying iron-oxide-based NPs for enhanced biocompatibility, biodegradability, colloidal stability, lowered toxicity, and more efficient and targeted delivery. This review covers iron-oxide-based NPs in cancer therapy, focusing on recent research advances in the use of ferrites. Methods for the synthesis of cubic spinel ferrites and the requirements for their considerations as potential nanocarriers in cancer therapy are discussed. The review highlights surface modifications, where functionalisation with specific biomolecules can deliver better efficiency. Finally, the challenges and solutions for the use of ferrites in cancer therapy are summarised.

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“…These biomolecules increase the specificity toward cellular targets, prevent the agglomeration of the particles and also decrease the cytotoxicity of these particles [6]. The most commonly used biomolecules are the natural and synthetic polymers [7][8][9], the aminoacids [10], the polyhydroxycarboxylic acids and the bile acids [11].…”

Section: Introductionmentioning

confidence: 99%

Structural, morphological and magnetic investigations on cobalt ferrite nanoparticles obtained through green synthesis routes

et al. 2021

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This paper describes for the first time two processing routes-the precursor method and the two-step wet chemical process-for the synthesis of magnetic cobalt ferrite using the Tamarindus indica fruit extract. These green approaches are eco-friendly, safe and efficient alternatives to classical chemical methods. The aqueous extract from tamarind fruit contains numerous metabolites (organic acids, aminoacids). All these bioactive components are able to chelate metal ions leading to the formation of the multimetallic complex (precursor of cobalt ferrite). The obtained precursor was characterized by Fourier transform infrared spectroscopy (FTIR), thermal analysis, X-ray diffraction analysis (XRD) and magnetic measurements. The structure, morphology and magnetic behavior of the cobalt ferrite samples prepared through both synthesis routes were investigated by various characterization techniques: FTIR, XRD, scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS), Mössbauer spectroscopy and magnetic measurements. XRD data confirmed that a cubic spinel structure was obtained for both ferrite powders with average crystallite size of 13 and 5 nm, respectively. The microstructure study by SEM revealed the formation of nanocrystallites assemblies using the precursor method and carbon-rich particles forming granulated micron-sized agglomerates, embedding ferrite nanocrystallites obtained through the two-step wet chemical process. Mössbauer spectroscopy results evidenced relaxation processes in the CoFe 2 O 4 samples at room temperature, and the main characteristics of the involved sublattices were derived. The magnetic investigation revealed a typical magnetic behavior for a spinel, with CoFe 2 O 4 nanoparticles ferrimagnetic at low temperature and superparamagnetic at room temperature.

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Leucine-coated cobalt ferrite nanoparticles: Synthesis, characterization and potential biomedical applications for drug delivery

Cited by 39 publications

References 26 publications

Study of Phase Transformation, Structures, Morphology, and Vibration of Ni-Zn-Co Ferrites Nanoparticles due to Annealing Temperature

Study of Phase Transformation, Structures, Morphology, and Vibration of Ni-Zn-Co Ferrites Nanoparticles due to Annealing Temperature

Advances in the Synthesis and Application of Magnetic Ferrite Nanoparticles for Cancer Therapy

Structural, morphological and magnetic investigations on cobalt ferrite nanoparticles obtained through green synthesis routes

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