Levels of scientific evidence of the quality of life in patients treated for oral cancer

Barrios, Rocío; Montero, Javier; González-Moles, Miguel-Ángel; Baca, Pilar; Bravo, Manuel

doi:10.4317/medoral.19052

Cited by 11 publications

(11 citation statements)

References 87 publications

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“…Finally, the follow-up period was not significantly associated with any of these parameters. This finding together with the results of other studies showing improvements in quality of life after a year [ 40 ], three years [ 37 ] or five years [ 10 , 12 , 13 ], suggest that the literature is inconclusive about a specific follow-up period associated with improved HRQOL or OHRQoL and also imply that the pattern of improvement over time may not be linear.…”

Section: Discussionmentioning

confidence: 76%

Oral and general health-related quality of life in patients treated for oral cancer compared to control group

Barrios

Bravo

Gil-Montoya

et al. 2015

Health and Quality of Life Outcomes

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BackgroundHealth-related quality of life (HRQoL) is gaining importance as a valuable outcome measure in oral cancer area. The aim of this study was to assess the general and oral HRQoL of oral and oropharyngeal cancer patients 6 or more months after treatment and compare them with a population free from this disease.MethodsA cross-sectional study was carried out with patients treated for oral cancer at least 6 months post-treatment and a gender and age group matched control group. HRQoL was measured with the 12-Item Short Form Health Survey (SF-12); oral HRQoL (OHRQoL) was evaluated using the Oral Health Impact Profile (OHIP-14) and the Oral Impacts on Daily Performances (OIDP). Multivariable regression models assessed the association between the outcomes (SF-12, OHIP-14 and OIDP) and the exposure (patients versus controls), adjusting for sex, age, social class, functional tooth units and presence of illness.ResultsFor patients (n = 142) and controls (n = 142), 64.1% were males. The mean age was 65.2 (standard deviation (sd): 12.9) years in patients and 67.5 (sd: 13.7) years in controls. Patients had worse SF-12 Physical Component Summary scores than controls even in fully the adjusted model [β-coefficient = −0.11 (95% CI: −5.12-(−0.16)]. The differences in SF-12 Mental Component Summary were not statistically significant. Regarding OHRQoL patients had 11.63 (95% CI: 6.77-20.01) higher odds for the OHIP-14 and 21.26 (95% CI: 11.54-39.13) higher odds for OIDP of being in a worse category of OHRQoL compared to controls in the fully adjusted model.ConclusionAt least 6 months after treatment, oral cancer patients had worse OHRQoL, worse physical HRQoL and similar psychological HRQoL than the general population.Electronic supplementary materialThe online version of this article (doi:10.1186/s12955-014-0201-5) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 76%

Oral and general health-related quality of life in patients treated for oral cancer compared to control group

Barrios

Bravo

Gil-Montoya

et al. 2015

Health and Quality of Life Outcomes

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“…Therefore, the decline in overall HRQOL was likely due to those oral sequelae of radiation. Importantly, these could lead to chewing and swallowing difficulty, and poor quality of life [ 33 ]. In contrast to the control group, subjects in the study group could maintain HRQOL score of those oral domains throughout RT, without significant decrease.…”

Section: Discussionmentioning

confidence: 99%

Nutri-jelly may improve quality of life and decrease tube feeding demand in head and neck cancer patients

Trachootham

Songkaew²,

Hongsachum

et al. 2014

Support Care Cancer

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PurposeEating difficulty is a critical and common problem in head and neck cancer patients undergoing radiotherapy (RT). It leads to poor quality of life and extensive tube feeding use. Nutri-jelly, a food gel with semisolid texture, water-releasing ability, and ready-to-eat by spoon, was recently developed to alleviate the trouble. However, its efficacy was unknown. This study investigated the potential effect of Nutri-jelly on health-related quality of life (HRQOL) and nasogastric tube feeding use.MethodsA prospective quasi-randomized patients-preference controlled trial was conducted in 74 head and neck cancer patients. Subjects in study and control groups (37 each) had similar baseline HRQOL and body mass index and undergone definitive radiotherapy (25–35 RT fractions, 5,000–7,000 cGy). Only study group received a 200-ml box of Nutri-jelly as daily supplement throughout radiotherapy. HRQOL was scored by validated questionnaires. The use of tube feeding was collected from medical records.ResultsFrom 11 to 35 RT fractions, the study group maintained higher overall HRQOL score than that of control group (p < 0.0001). Multiple physiologic and psychological aspects of HRQOL especially swallowing difficulty and overall eating problems were significantly improved in study as compared to control group. Promisingly, the percentage of tube feeding use in study group (13.5 %) was dramatically lower than control group (48.6 %).ConclusionsContinuous supplementation of Nutri-jelly throughout radiotherapy may improve HRQOL and reduce tube feeding demand in head and neck cancer patients who preferred to take them. Nutri-jelly could be an alternative for head and neck cancer patients who have eating difficulty during radiotherapy.Electronic supplementary materialThe online version of this article (doi:10.1007/s00520-014-2488-5) contains supplementary material, which is available to authorized users.

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“…A recent review has been done about studies that looked at the HRQoL and OHRQoL of patients treated for oral and oropharyngeal cancer ( 8 ). However, little is known about the relationship between HRQoL and OHRQoL, because their findings of the studies were inconclusive.…”

Section: Introductionmentioning

confidence: 99%

Association between general and oral health-related quality of life in patients treated for oral cancer

Barrios¹,

Tsakos²,

Gil-Montoya³

et al. 2015

Med Oral

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BackgroundLess is known about the association between general health-related quality of life (HRQoL) and oral HRQoL (OHRQoL) among patients with specific diseases. The aim of this study was to assess the association between patient-centered outcome measurements (HRQoL and OHRQoL) of oral cancer patients at least 6 months after treatment.Material and MethodsHRQoL was measured with the 12-Item Short Form Health Survey (SF-12); OHRQoL was evaluated using the Oral Health Impact Profile (OHIP-14) and the Oral Impacts on Daily Performances (OIDP).ResultsHigher OHRQoL scores were associated with lower SF-12 domains scores. The OHIP-14 explained 16.5 % of the total variance of SF-12 Physical Component Summary (PCS) and the OIDP explained 16.1 %. In the SF-12 Mental Component Summary (MCS), the total variance explained was 23.9 % by the OHIP-14 and 21.8 % by the OIDP.ConclusionsThere was a significant association between long-term OHRQoL and HRQoL in oral and oropharyngeal cancer patients. These results may help to carry out new interventions aiming to improve patient´s life overall. Key words:Mouth neoplasms, quality of life, health status, oral health.

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Levels of scientific evidence of the quality of life in patients treated for oral cancer

Cited by 11 publications

References 87 publications

Oral and general health-related quality of life in patients treated for oral cancer compared to control group

Oral and general health-related quality of life in patients treated for oral cancer compared to control group

Nutri-jelly may improve quality of life and decrease tube feeding demand in head and neck cancer patients

Association between general and oral health-related quality of life in patients treated for oral cancer

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