Background: Educational material is frequently used by health providers to inform adolescences about the health hazards of hookah. However, little attention has been paid to the readability and suitability of these adolescent educational materials. Objectives: The aim of this study was to determine the readability and suitability of adolescent educational material in preventing hookah smoking. Patients and Methods: Multiple authoritative resources were chosen for the design and preparation of educational material and were then tailored to the target group. Readability was measured by using the readability assessment of materials (RAM); and suitability was determined by the suitability assessment of materials (SAM) that considers characteristics such as content, graphics, layout/topography, and cultural appropriateness. Fifteen reviewers, including 10 adolescents and 5 health experts scored the educational material. Results: The mean readability score ± standard deviation (SD) of the educational media was 9 ± 1.9, 10 ± 1.1, and 9 ± 1.7, for the pamphlet, brochure, and poster, respectively, which were increased to 15 ± 1.3, 17 ± 0.7, and 16 ± 1.5 after tailoring the content. The average SAM scores before and after tailoring the content were 79% for the pamphlet, which was increased to 90%; 81% for the brochure, which was increased to 93%; and 79% for the poster, which was increased to 93%. The increase in all scores was significant (P < 0.05). The final tailored educational material was rated "superior media" on the SAM ratings. Conclusions: The findings indicated that the readability and suitability of the educational material were increased. Compliance with these recommendations may increase the likelihood of consumer perception and recall.