Levels of Vitamin D and Calcium as Risk Factors for Chronic Periodontitis

Abstract

Objectives:This study was conducted to estimate, compare and correlate the serum and salivary vitamin D3 (VitD3) in form of [25 (OH) D] and calcium (Ca) levels in healthy subjects and chronic periodontitis (C.P) patients. Subjects and methods:The study included 50 subjects divided into 2 groups: 30 C.P patients and 20 periodontally healthy subjects. Clinical examination was performed for all subjects, salivary and blood samples were collected from all 50 subjects. Salivary and serum VitD3 levels were assessed by ELISA assay, while Ca was measured colouremetrically.Results : Salivary and serum VitD3 levels were significantly higher in control subjects compared to C.P patients. Salivary Ca level was significantly higher in C.P group than control group but serum Ca level showed insignificance higher level in control group than C.P patients. No significance correlation was observed except for saliva and serum VitD3 levels there was a statistical significance correlation in the control group. Conclusion:Low salivary and serum VitD3 and high salivary Ca levels are associated with periodontitis, they might be considered as risk factors for periodontal diseases but this association need to be confirmed in more future studies. , et al.: Plasma 25 hydroxy vitamin D concentrations and periodontal disease in postmenopausal women. J Periodontol.; 84: 1243-56, 2013