Lichen striatus after COVID-19

Herzum, Astrid; Viglizzo, Gianmaria; Gariazzo, Lodovica; Ferro, Jacopo; Vellone, Valerio Gaetano; Occella, C.

doi:10.1016/j.clindermatol.2022.09.006

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…4 Also, the theory of an immune pathogenesis of AA is supported by the high association rate with immune-mediated diseases such as thyroiditis, type I diabetes, and vitiligo, which, in turn, have also been associated with COVID-19 infection. [4][5][6] Though a just casual association must be considered, the temporal association evidenced between COVID-19 infection and the new onset of AA of our patients reflects the temporal line of events described in other literature reports and speak in favor of a causative link. 2,3 Lately, the close attention paid to COVID-19 infection permitted to observe numerous possible associations with cutaneous autoimmune manifestations.…”

Section: E T T E R S T O T H E E D I T O R Pediatric Alopecia Areata ...supporting

confidence: 78%

“…2,3 Lately, the close attention paid to COVID-19 infection permitted to observe numerous possible associations with cutaneous autoimmune manifestations. 1,5,6 Possibly, AA has always been virally triggered, but the increased consciousness toward the COVID-19 infection may have allowed to document otherwise underestimated associations.…”

Section: E T T E R S T O T H E E D I T O R Pediatric Alopecia Areata ...mentioning

confidence: 99%

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Pediatric alopecia areata following COVID‐19 infection

Herzum

Viglizzo

Gariazzo

et al. 2023

J of Cosmetic Dermatology

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Section: E T T E R S T O T H E E D I T O R Pediatric Alopecia Areata ...supporting

confidence: 78%

Section: E T T E R S T O T H E E D I T O R Pediatric Alopecia Areata ...mentioning

confidence: 99%

Pediatric alopecia areata following COVID‐19 infection

Herzum

Viglizzo

Gariazzo

et al. 2023

J of Cosmetic Dermatology

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“…Jones et al reviewed the literature of LS after vaccination (five cases) and reported an additional patient whose eruption occurred after hepatitis B vaccination [ 84 ]. Most recently, a small case series of four children with lichen striatus following COVID-19 infection was reported [ 85 ].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Vaccine-Induced Lichenoid Eruptions—Clinical and Histopathologic Spectrum in a Case Series of Fifteen Patients with Review of the Literature

et al. 2023

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Lichen planus is a distinctive mucocutaneous disease with well-established clinical and histopathologic criteria. Lichenoid eruptions closely resemble lichen planus and may sometimes be indistinguishable from it. Systemic agents previously associated have included medications, viral infections and vaccines. Sporadic case reports of lichen planus and lichenoid reactions associated with COVID-19 vaccines have recently emerged. Herein, we review the world literature (31 patients) and expand it with a case series of 15 patients who presented with vaccine-induced lichenoid eruption (V-ILE). The spectrum of clinical and histopathologic findings is discussed with emphasis on the subset whose lesions manifested in embryologic fusion lines termed lines of Blaschko. This rare Blaschkoid distribution appeared in seven of the 46 patients studied. Of interest, all seven were linked to the mRNA COVID-19 vaccines. We believe that all lichenoid eruptions should be approached with a heightened index of suspicion and patients should be specifically questioned with regards to their vaccination history. When diagnosed early in its course, V-ILE is easily treated and resolves quickly in almost all patients with or without hyperpigmentation. Additional investigative studies regarding its immunopathology and inflammatory signaling pathways may offer insight into other Th1-driven autoimmune phenomena related to COVID-19 vaccination.

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“…Despite an improved understanding of the pathogenesis underlying inherited disorders of keratinisation (DOK), management remains largely symptomatic with emollients, keratolytic agents, topical vitamin D3 analogues and retinoids 1,2 . Currently, there is an increasing but exiguous literature on biologic therapy for DOK 3,4 . This review aimed to determine the comparative efficacy and safety of anti‐inflammatory biologics for treating inherited ichthyosis and palmoplantar keratodermas.…”

Section: Introductionmentioning

confidence: 99%

Biologics for inherited disorders of keratinisation: A systematic review

Chen,

Flanagan,

Sebaratnam

et al. 2023

Aust J Dermatology

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Background/ObjectivesRecent literature highlights the potential of biologics in the management of inherited disorders of keratinisation. In this study, we conducted a systematic review of existing literature on treatment outcomes of inherited keratinisation disorders treated with biologics.MethodsEligible records were retrieved through searches of the electronic databases MEDLINE, Embase, PubMed and Scopus. Databases were searched from inception to July 2023 for eligible records. A snowballing method was employed to search the references of the retrieved records for the identification of potentially relevant articles.ResultsOne hundred and four eligible studies consisting of a total of 166 patients with an inherited disorder of keratinisation were included. Patients had a median age of 19 years (range: 0.5 to 70 years). The most common disorders were Netherton syndrome (n = 63; 38%), autosomal recessive congenital ichthyoses (n = 27; 16%), CARD14‐associated papulosquamous eruptions (n = 17; 10%) and familial pityriasis rubra pilaris (PRP) (n = 15; 9%).Of the 207 times biologics were employed, the three most frequently employed biologics were secukinumab (n = 47; 23%), dupilumab (n = 44; 21%) and ustekinumab (n = 37; 18%). Complete remission was observed in 10 (5%) instances, partial remission in 129 (62%), no or limited response to biologic therapy in 68 (32%) cases, and results are still pending in one case. A total of 33 adverse events were reported.ConclusionsWhilst biologics may be considered in cases of inherited keratinisation disorders recalcitrant to standard therapy, definitive conclusions are prohibited by the low‐level of evidence and substantial heterogeneity in methodology across the included studies. Establishment of consensus definitions, and randomised clinical trials may help ascertain the efficacy and safety of biologic therapy in this context and establish the best agent and dosing protocol for each disorder.

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Lichen striatus after COVID-19

Cited by 6 publications

References 6 publications

Pediatric alopecia areata following COVID‐19 infection

Pediatric alopecia areata following COVID‐19 infection

COVID-19 Vaccine-Induced Lichenoid Eruptions—Clinical and Histopathologic Spectrum in a Case Series of Fifteen Patients with Review of the Literature

Biologics for inherited disorders of keratinisation: A systematic review

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