Lichttaglänge und Oxytetracyclin‐Blutplasmaspiegel bei Legehennen nach Verabreichung von Oxytetracyclin in therapeutischer Dosierung über das Futter

Kh, Hinz; Kw, Lai; Lüders, H

doi:10.1111/j.1439-0450.1972.tb00383.x

Cited by 3 publications

(1 citation statement)

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“…Work already done on this antibiotic family indicates that they are more soluble, what would explain their concentration in tissues (Roudaut, 1997). They also have an affinity with vascular tissue rich in calcium (Hinz et al, 1972).…”

Section: Presence Of Residues Of Tetracyclines In Thigh and Sternum Mmentioning

confidence: 99%

Detection of antibiotics residues in meat of reformed and marketed laying hens in southern Benin

Mensah¹,

Ahissou²,

Koudandé³

et al. 2012

Int. J. Bio. Chem. Sci

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The presence in meat products of antibiotic residues is of toxicological risks for the consumer. In order to protect consumers through the safety of meat from reformed and marketed laying hens, a qualitative study was conducted in southern Benin. The study was conducted in twenty laying hen farms in Abomey-Calavi, Ouidah and Porto Novo towns. The survey identified antibiotics used by farmers. In each farm, five reformed chickens ready to be marketed were randomly selected. On each bird, the sternum and right thigh were collected and analyzed by the microbiological method of four plates at the Laboratory. Results showed that farmers use eight families of antibiotics: aminoglycosides, diaminopyridines, macrolides, polypeptides, quinolones second and third generation, sulfonamides and tetracyclines. Residues of tetracyclines and aminoglycosides were found only in Abomey-Calavi town with respective proportions of 25.71 ± 10.14% and 21.41± 9.93% while residues of macrolides were observed in three localities which are Abomey-Calavi, Ouidah and Porto Novo, with respective rates of 65.71 ± 9.92%, 46 ± 15.5% and 20 ± 8.36%. From the above results, we recommend to veterinarians the efficient use of antibiotics and to poultry farmers the respect of withdrawal period.

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Section: Presence Of Residues Of Tetracyclines In Thigh and Sternum Mmentioning

confidence: 99%

Detection of antibiotics residues in meat of reformed and marketed laying hens in southern Benin

Mensah¹,

Ahissou²,

Koudandé³

et al. 2012

Int. J. Bio. Chem. Sci

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Excretion of oxytetracycline in eggs after medication of laying hens

Roudaut

Moretain

Boisseau

1987

Food Additives and Contaminants

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The kinetics of oxytetracycline elimination into eggs were determined separately for albumen and yolk after oral administration through either drinking water (0.1-0.25 and 0.5 g/l for 5 days) or feed (300 and 600 ppm for 7 days) or after intramuscular injections (3 X 15 mg/kg body weight and 3 X 30 mg/kg body weight), 24 hours apart. Residues were assayed by a microbiological agar diffusion method, with Bacillus cereus as test-organism. The detection threshold was 0.07 micrograms/g for albumen and 0.2 micrograms/g for yolk. In all cases, the elimination period lasted longer for the yolk; it varied between 0 and 10 days after treatment was discontinued, according to administration routes and dosages. The conditions of oxytetracycline utilization in laying hens are discussed. The oral route only might be used to adhere to the proposals presented by the Joint FAO/WHO Expert Committee on Food Additives.

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Blut‐ und Gewebespiegel von Sulfamethazin und Sulfaquinoxalin bei Broilern nach Verabreichung der Medikamente über das Trinkwasser* Ein Beitrag zur Massentherapie des Geflügels

Lüders

Lai

Hinz

1974

Zentralblatt für Veterinärmedizin Reihe B

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Zusammenfassung Broiler verschiedenen Alters erhielten bei 20 Stunden Kunstlicht 0,1% Sulfamethazin‐ (SM) oder 0,05% Sulfaquinoxalin‐ (SQ) ‐haltiges Trinkwasser über 3 Tage ad libitum verabreicht. Am 3. Tag nach Versuchsbeginn wurden zu verschiedenen Zeitpunkten das freie Sulfonamid im Blut und nach Absetzen der Medikamente in der Leber und der Muskulatur bestimmt. Weiterhin wurde der Einfluß der verabreichten Sulfonamide auf die Trinkwasser‐ und Futteraufnahme kontrolliert. Es konnte nachgewiesen werden, daß SM (17–25%) eine höhere Reduktion der Trinkwasseraufnahme (und damit auch der Futteraufnahme) als SQ (6–15%) bewirkt. Die Blutspiegel für beide Medikamente lagen bei den jüngeren Broilern signifikant höher als bei den älteren. Der postulierte, therapeutisch wirksame Mindestwert von 5 mg% wurde nur bei den SM‐Blutwerten einiger 40 Tage alter Broiler nicht erreicht. Nach der SQ‐Aufnahme waren erheblich höhere Blutwerte als nach SM‐Gaben nachweisbar. 72 Stunden nach Entzug der Sulfonamide konnten keine Sulfonamidrückstände im Blut, in der Leber und in der Muskulatur mehr nachgewiesen werden. Summary Blood and tissue levels of Sulphamezathine and Sulphaquinoxaline in broilers after administering medicaments in the drinking water Broilers of varying ages received, under conditions of 20 hours artificial light, 0.1% Sulphamezathine (SM) or 0.05% Sulphaquinoxaline (SQ) in the drinking water (given ad lib) for 3 days. On the 3rd day and at various times the levels of free Sulphonamides were measured in the blood and, at autopsy, the levels in liver and muscles. The effect of the Sulphonamides on water and food intake was also studied. SM resulted in a greater reduction (17–25%) of water intake (and of food) than did SQ (6–15%). The blood levels of both drugs were significantly higher in younger broilers than in older ones. The postulated minimal therapeutic dose of 5 mg.% was only not reached in the case of the SM levels of some of the 40‐day‐old birds. SQ gave higher blood levels than SM. No Sulphonamide residue could be detected in blood, liver or muscle 72 hours after withdrawal of the drugs. Résumé Taux de sulfamethazine et de sulfaquinoxaline dans le sang et les tissus chez des «Broilers» après application de médicaments avec l'eau de boisson On a donné ad libitum à des «Broilers» d'âges différents, pendant 3 jours et avec une lumière artificielle de 20 heures, une eau de boisson contenant 0,1% de sulfamethazine (SM) ou 0,05% de sulfaquinoxaline (SQ). On a déterminé au troisième jour après le début de l'essai et à différents moments le sulfonamide libre dans le sang et, après l'arrêt du médicament, dans le foie et la musculature. On a contrôlé en outre l'influence du sulfonamide appliqué sur la consommation de l'eau et du fourrage. Il a été constaté que SM (17–25%) provoque une plus forte réduction de la consommation d'eau (également du fourrage) que SQ (6–15%). Le taux sanguin fut pour les deux médicaments significativement plus élevés chez les jeues «Broilers» que chez les animaux plus âgés. La valeur thérape...

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Lichttaglänge und Oxytetracyclin‐Blutplasmaspiegel bei Legehennen nach Verabreichung von Oxytetracyclin in therapeutischer Dosierung über das Futter

Cited by 3 publications

References 11 publications

Detection of antibiotics residues in meat of reformed and marketed laying hens in southern Benin

Detection of antibiotics residues in meat of reformed and marketed laying hens in southern Benin

Excretion of oxytetracycline in eggs after medication of laying hens

Blut‐ und Gewebespiegel von Sulfamethazin und Sulfaquinoxalin bei Broilern nach Verabreichung der Medikamente über das Trinkwasser* Ein Beitrag zur Massentherapie des Geflügels

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