n-Propanol, as an important chemical
raw material, is used
as a solvent and intermediate in chemical industrial production and
drug synthesis. In chemical production, alcohol and water easily form
an azeotrope which is difficult to separate. In this work, a method
of dehydration of n-propanol by pervaporation-assisted
extractive distillation is proposed. Glycerol is selected as entrainer
by quantum chemical calculation. A combined pervaporation unit with
cellophane as a membrane is designed to separate the entrainer and
water. The pervaporation unit is developed by using the Aspen Custom
Modeler. Based on the minimum total annual cost, the extractive distillation
process, feed-preheating extractive distillation process, and pervaporation-assisted
extractive distillation process are optimized. The results show that
the total annual cost of pervaporation-assisted extractive distillation
is minimum and can reduce the total annual cost by 21.25%, compared
with extractive distillation. Life cycle analysis is used to evaluate
the environmental impact of processes. The results of environmental
performance evaluation show that the pervaporation-assisted extractive
distillation has the least environmental impact. Thus, the integration
technology of membrane and distillation is of great significance in
the sustainable process of chemical design and development.