Life span of circulating blood cells in ginbuna crucian carp (Carassius auratus langsdorfii)

Induction of DNA base damage and strand breaks in peripheral erythrocytes and the underlying mechanism in goldfish (Carassius auratus) exposed to monocrotophos

“…Such difference may be due to the different exposure dose of monocrotophos or the distinct life span of erythrocytes, which varies among species over a range of 80-500 days with an erythrocyte mutation period of 17-23 days (Dinnen et al 1988;Avery et al 1992;Fischer et al 1998;Ç avaş and Könen 2007). Ali and Kumar (2008) reported that DNA damage (the percentage of DNA in comet tails) in the gill, kidney, and lymphocytes of C. punctatus exposed to 1.59-4.78 mg/L monocrotophos pesticide (36 % effective concentration) decreased gradually after reaching peak values at 96 h. Thus, compared with C. punctatus, goldfish with the most serious DNA damage occurring at 48 h exhibited a higher DNA repair ability.…”

Effect of environmental temperature onin vitrocell-mediated cytotoxicity (CMC) and graft-versus-host reaction (GVHR) in ginbuna crucian carp (Carassius auratus langsdorfii)

“…In the present experiments one of four fish reared at 25 C showed severe clinical signs of GVHD but finally recovered, and fish kept at 15 C showed weak GVHD but only one of four fish died. The in vivo half life of lymphocytes from ginbuna crucian carp is less than 23 days (Fischer et al, 1998b). However, parallel experiments have shown, that S3n PBL can proliferate in S4n recipients to a certain extent (unpublished data).…”

Cell-mediated cytotoxicity in isogeneic ginbuna crucian carp

“…Ginbuna have several advantages over artificially gynogenetic and/or inbred fishes in that they weigh 40-50 g at one year old, are easy to maintain, and tolerate handling. By using ginbuna, it has been possible to study the variability of immune reactivity in isogeneic animals (Nakanishi & Onozato, 1990), kinetics of transfer of immunity by immune leucocytes (Nakanishi, 1987a), comparison of transferability of immune pronephric cells in isogeneic, allogeneic and xenogeneic transfer systems (Nakanishi, 1987b) and the life span of circulating blood cells (Fischer et al, 1998b).…”