Lifestyle modification for obstructive sleep apnoea

Shneerson, John M.; Wright, John

doi:10.1002/14651858.cd002875

Cited by 70 publications

(37 citation statements)

References 20 publications

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“…The way forward is to integrate both clinical training and management, to ensure interdisciplinary skills in the full range of OSA therapeutics in one setting. It will be important to underpin this disruption of therapeutic silos by more randomised controlled trials built from the current knowledge base, to further unveil the role of lifestyle modification and exercise in the management of OSA [92,93]. While there is a clear benefit in employing intensive lifestyle interventions with or without CPAP therapy for the management of the obese OSA patient, further exploration into the most effective lifestyle prescription (encompassed by a specific diet and exercise programme) is warranted.…”

Section: Osa and Liver Damagementioning

confidence: 99%

Sleep apnoea and metabolic dysfunction

Bonsignore¹,

Borel²,

Machan³

et al. 2013

Eur Respir Rev

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Obstructive sleep apnoea (OSA) is a highly prevalent condition often associated with central obesity. In the past few years, several studies have analysed the potential independent contribution of OSA to the pathogenesis of metabolic abnormalities, including type 2 diabetes, the metabolic syndrome and nonalcoholic fatty liver disease. New perspectives in OSA patient care have been opened by the promotion of lifestyle interventions, such as diet and exercise programmes that could improve both OSA and the metabolic profile. The rich clinical literature on this subject, together with the growing amount of data on pathophysiological mechanisms provided by animal studies using the chronic intermittent hypoxia model, urged the organising Committee of the Sleep and Breathing meeting to organise a session on sleep apnoea and metabolic dysfunction, in collaboration with the European Association for the Study of Diabetes. This review summarises the state-of-the-art lectures presented in the session, more specifically the relationship between OSA and diabetes, the role of OSA in the metabolic consequences of obesity, and the effects of lifestyle interventions on nocturnal respiratory disturbances and the metabolic profile in OSA patients. @ERSpublications Treatment of obesity and metabolic diseases through diet and exercise should be part of OSA management besides CPAP

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Section: Osa and Liver Damagementioning

confidence: 99%

Sleep apnoea and metabolic dysfunction

Bonsignore¹,

Borel²,

Machan³

et al. 2013

Eur Respir Rev

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“…However, the response to weight loss is variable, weight loss is difficult to maintain long-term and SRBD may recur even after surgically induced weight loss (Pillar et al, 1994;Strobel and Rosen, 1996). Furthermore, studies of weight loss are severely deficient in regard to their design and follow-up (Strobel and Rosen, 1996;Shneerson and Wright, 2001). As a result, the use of continuous positive airway pressure (CPAP), which appears to be the most effective therapy for symptoms of OSA, has become the treatment of choice.…”

Section: Introductionmentioning

confidence: 99%

The effect of an increased intake of vegetables and fruit on weight loss, blood pressure and antioxidant defense in subjects with sleep related breathing disorders

et al. 2007

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Objective: To assess the effect of an increased consumption of vegetables and fruit on body weight, risk factors for cardiovascular disease (CVD) and antioxidant defense in obese patients with sleep-related breathing disorders (SRBD). Design: Randomized, controlled trial of an intervention to increase the intake of vegetables to 400 g/day and fruit to 300 g/day. Dietary intake was calculated from a food frequency questionnaire. Antioxidant status was assessed with the ferric-reducing/ antioxidant power (FRAP) assay. Plasma carotenoids were biomarkers for the intake of vegetables and fruit. Setting: A hospital clinic preventing risk factors for CVD. Subjects: Subjects were 103 men and 35 women with a body mass index of 36.775.8 kg/m 2 of which 57 (86%) in the control and 68 (94%) in the intervention group completed the study. Intervention: Group-based behavioral program during 3 months. Results: The mean between group differences in body weight was À2.0% (95% CI À3.6, À0.5), Po0.0001. The mean between group difference in systolic and diastolic blood pressure (BP) was À7.1 mm Hg (95% CI: À11.6, À2.6), P ¼ 0.0022 and À3.9 mm Hg (95% CI: À7.0, À0.9), P ¼ 0.0120, respectively. The mean change in daily intake of vegetables and fruit was 12 g (95% CI: À33, 57) and À4 g (95% CI: À79, 71) versus 245 g (95% CI: 194, 296) and 248 g (95% CI: 176, 320) in the control and intervention groups, respectively. This was reflected in higher concentrations of a-carotene and b-carotene. No change in FRAP was seen. In a multiple regression analysis the change in intake of vegetables was a significant contributor (R adj 2 ¼ 0.073 (95% CI: 0.019, 0.214)) to the change in weight. Conclusion: Targeted dietary advice to increase the intake of vegetables and fruit among subjects with SRBD contributed to weight reduction and reduced systolic and diastolic BP, but had no effect on antioxidant defense measured with FRAP. Sponsorship: None.

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“…OSA and OHS show strong associations with lifestyle factors [14][15][16][17] ; however, there is currently no evidence that population-based lifestyle changes, including general weight reduction programs, have any effect on the occurrence and consequences of SDB (OSA/OHS). There is considerable evidence that CPAP use reduces cardiovascular morbidity, mortality, and road traffic accidents traffic consequences in patients with OSA.…”

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confidence: 99%