2007
DOI: 10.1039/b704741j
|View full text |Cite
|
Sign up to set email alerts
|

Ligand-based backbone modifications for metal-chelating nucleic acids

Abstract: Ligands were incorporated into the backbone of DNA for nucleoside replacements, and the binding of metal ions, such as Cu2+, Pt2+ and Pd4+, was shown to influence stability of the resulting duplexes.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

2008
2008
2016
2016

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 6 publications
(3 citation statements)
references
References 50 publications
0
3
0
Order By: Relevance
“…Pt 2+ coordination can increase the stability of such a duplex [61]. Interesting work published by Sugimoto demonstrated the use of metals to assemble higher order structures [62].…”
Section: Dna Modified With Terpyridine Bipyridine and Phenanthrolinementioning
confidence: 97%
“…Pt 2+ coordination can increase the stability of such a duplex [61]. Interesting work published by Sugimoto demonstrated the use of metals to assemble higher order structures [62].…”
Section: Dna Modified With Terpyridine Bipyridine and Phenanthrolinementioning
confidence: 97%
“…A metal-binding bipyridyl unit was inserted into a nucleotide oligomer by Knagge and Wilker. 23 Duplexes with unmodified strands were stabilised to different extents by the insertion of different metal ions either through their cationic charge or hydrogen bonding, enabling the possibility of tuning duplex stability.…”
Section: Backbone Modificationsmentioning
confidence: 99%
“…The incorporation of unnatural ligating groups for metal ions into DNA facilitates the formation of these nucleic acid/metal ion hybrid materials. Such ligands may be incorporated as base modified nucleotides or as non-nucleosidic ligands , . Ligands may be appended to either the 5′ or 3′-termini of DNA or, alternately, incorporated in midsequence of the DNA ,,, .…”
Section: Introductionmentioning
confidence: 99%