Light in the Fungal World: From Photoreception to Gene Transcription and Beyond

Corrochano, Luis M.

doi:10.1146/annurev-genet-120417-031415

Cited by 103 publications

(107 citation statements)

References 142 publications

(236 reference statements)

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“…Such spontaneous genetic changes were previously reported to occur at an elevated frequency in Z. tritici during in vitro propagation (Möller et al , ). WC‐1 together with WC‐2 composes the White Collar complex (WCC) and acts as a transcription factor whose activity is regulated by light (Corrochano, ; He et al . ; Linden and Macino, ).…”

Section: Discussionmentioning

confidence: 99%

The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici

Habig

Bahena-Garrido

Barkmann

et al. 2019

Molecular Plant Pathology

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Summary Zymoseptoria tritici is a filamentous fungus causing Septoria tritici blotch in wheat. The pathogen has a narrow host range and infections of grasses other than susceptible wheat are blocked early after stomatal penetration. During these abortive infections, the fungus shows a markedly different gene expression pattern. However, the underlying mechanisms causing differential gene expression during host and non‐host interactions are largely unknown, but likely include transcriptional regulators responsible for the onset of an infection programme in compatible hosts. MoCOD1, a member of the fungal Zn(II)2Cys6 transcription factor family, has been shown to directly affect pathogenicity in the rice blast pathogen Magnaporthe oryzae. Here, we analyse the role of the putative transcription factor Zt107320, a homologue of MoCOD1, during infection of compatible and incompatible hosts by Z. tritici. We show for the first time that Zt107320 is differentially expressed in host versus non‐host infections and that lower expression corresponds to an incompatible infection of non‐hosts. Applying reverse genetics approaches, we further show that Zt107320 regulates the dimorphic switch as well as the growth rate of Z. tritici and affects fungal cell wall composition in vitro. Moreover, ∆Zt107320 mutants showed reduced virulence during compatible infections of wheat. We conclude that Zt107320 directly influences pathogen fitness and propose that Zt107320 is involved in the regulation of growth processes and pathogenicity during infection.

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Section: Discussionmentioning

confidence: 99%

The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici

Habig

Bahena-Garrido

Barkmann

et al. 2019

Molecular Plant Pathology

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“…As fungi commonly sense light to indicate the presence of deleterious ultraviolet (UV) radiation, the light-induced survivability through UV damage is recognized as a marker response to light signal in fungi [35,36]. In the present study, the survival of serially diluted spores of all the tested strains was similarly poor if the fungal cultures were kept in the dark after UV-C treatment.…”

Section: The Marker Responses To Light Signal Are Mediated By Wcc Andmentioning

confidence: 67%

The Photoreceptor Components FaWC1 and FaWC2 of Fusarium asiaticum Cooperatively Regulate Light Responses but Play Independent Roles in Virulence Expression

et al. 2020

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Fusarium asiaticum belongs to one of the phylogenetical subgroups of the F. graminearum species complex and is epidemically predominant in the East Asia area. The life cycle of F. asiaticum is significantly regulated by light. In this study, the fungal blue light receptor white collar complex (WCC), including FaWC1 and FaWC2, were characterized in F. asiaticum. The knockout mutants ΔFawc1 and ΔFawc2 were generated by replacing the target genes via homologous recombination events. The two mutants showed similar defects in light-induced carotenoid biosynthesis, UV-C resistance, sexual fruiting body development, and the expression of the light-responsive marker genes, while in contrast, all these light responses were characteristics in wild-type (WT) and their complementation strains, indicating that FaWC1 and FaWC2 are involved in the light sensing of F. asiaticum. Unexpectedly, however, the functions of Fawc1 and Fawc2 diverged in regulating virulence, as the ΔFawc1 was avirulent to the tested host plant materials, but ΔFawc2 was equivalent to WT in virulence. Moreover, functional analysis of FaWC1 by partial disruption revealed that its light–oxygen–voltage (LOV) domain was required for light sensing but dispensable for virulence, and its Zinc-finger domain was required for virulence expression but not for light signal transduction. Collectively, these results suggest that the conserved fungal blue light receptor WCC not only endows F. asiaticum with light-sensing ability to achieve adaptation to environment, but it also regulates virulence expression by the individual component FaWC1 in a light-independent manner, and the latter function opens a way for investigating the pathogenicity mechanisms of this important crop disease agent.

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“…The responses to the light signal are very diverse between fungal species and can be either up-or down-regulative, depending on duration, intensity and spectral characteristics of the light fluence (Tisch and Schmoll 2010;Fuller et al 2015;Corrochano 2019). It is still impossible to predict a total range of photoinduced effects for a certain fungal genus, or family, or even class.…”

Section: Discussionmentioning

confidence: 99%

Long-lasting eﬀects of red and blue light exposure on the growth of soil fungi

Vinnikova

2020

Acta Biol Szeged

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The experimental assessment of inter-species difference in long lasting effects produced in fungi by a brief exposure to the monochromatic light was performed. 24-h cultures grown from 1 mm mycelium fragments of Alternaria alternata, Aspergillus clavatus, Fusarium fujikuroi, Penicillium citrinum and Trichoderma viride were exposed for 30 min to blue light (BL, 450 nm) or red light (RL, 660 nm) and cultured for the next 10 days. Radial growth rate, conidial yield and germination, contents of proteins and phenolsand fungal antibacterial activity were estimated. BL- or RL-exposure did not essentially affect the ﬁnal size of colonies of A. clavatus but delayed the growth of P. citrinum and stimulated it in A. alternata and F. fujikuroi; these changes were more profound after BL, than after RL. In T. viride the BL exposure led to a remarkable delay of growth, whereas the RL signiﬁcantly increased the growth rate. Photo-induced changes in the conidial yield, conidial germination, contents of proteins and phenols also were dependent on the light wavelength and showed strong inter-species heterogeneity. Fungal antibacterial activity in exposed cultures was similar to the unexposed control. The observed effects are indicative targets for future research of possible molecular regulatory mechanisms underlying the photobiology in different fungal taxons.

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Light in the Fungal World: From Photoreception to Gene Transcription and Beyond

Cited by 103 publications

References 142 publications

The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici

The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici

The Photoreceptor Components FaWC1 and FaWC2 of Fusarium asiaticum Cooperatively Regulate Light Responses but Play Independent Roles in Virulence Expression

Long-lasting eﬀects of red and blue light exposure on the growth of soil fungi

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