Light-triggered topological programmability in a dynamic covalent polymer network

Zou, Weike; Jin, Binjie; Wu, Yi; Song, Huijie; Luo, Yingwu; Huang, Feihe; Qian, Jin; Zhao, Qian; Xie, Tao

doi:10.1126/sciadv.aaz2362

Cited by 97 publications

(111 citation statements)

References 39 publications

Supporting

Mentioning

111

Contrasting

Order By: Relevance

“…We next resort to a photobase generator that can provide spatio-temporal release of a transesterification catalyst. Specifically, we employ a photobase generator that upon UV irradiation can release a strong organic base 1,5,7-triazabicyclo[4.4.0]dec-5-ene 29 . The catalyst amount can be controlled by the light irradiation time.…”

Section: Resultsmentioning

confidence: 99%

“…All chemicals were used as received. The photobase generator was synthesized according to the literature 29 .…”

Section: Methodsmentioning

confidence: 99%

“…As elegant as the approaches are, the requirement for external molecules to participate the process limits it to non-crosslinked polymer solutions/polymer melts. The concept of topological isomerizable network (TIN) 29 , by contrast, allows topological shifting within a "fully enclosed" solid material, that is, without participation of external reagents. This isomerization mechanism typically requires highly delicate design to introduce network heterogeneity.…”

mentioning

confidence: 99%

“…This isomerization mechanism typically requires highly delicate design to introduce network heterogeneity. For instance, a TIN consisting of a permanent network frame and dynamic grafted long chains can isomerize from a grafting network into a brush network 29 . From a design standpoint, such a hybrid network (permanent mainframe and dynamic grafted chain) is quite specific and unusual.…”

mentioning

confidence: 99%

See 3 more Smart Citations

On demand shape memory polymer via light regulated topological defects in a dynamic covalent network

et al. 2020

Self Cite

View full text Add to dashboard Cite

The ability to undergo bond exchange in a dynamic covalent polymer network has brought many benefits not offered by classical thermoplastic and thermoset polymers. Despite the bond exchangeability, the overall network topologies for existing dynamic networks typically cannot be altered, limiting their potential expansion into unexplored territories. By harnessing topological defects inherent in any real polymer network, we show herein a general design that allows a dynamic network to undergo rearrangement to distinctive topologies. The use of a light triggered catalyst further allows spatio-temporal regulation of the network topology, leading to an unusual opportunity to program polymer properties. Applying this strategy to functional shape memory networks yields custom designable multi-shape and reversible shape memory characteristics. This molecular principle expands the design versatility for network polymers, with broad implications in many other areas including soft robotics, flexible electronics, and medical devices.

show abstract

Section: Resultsmentioning

confidence: 99%

“…All chemicals were used as received. The photobase generator was synthesized according to the literature 29 .…”

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

On demand shape memory polymer via light regulated topological defects in a dynamic covalent network

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…However, the relatively poor mechanical behavior of hydrogels remains a challenge, owing to the lack of an efficient energy dissipation mechanism, impeding their use in many application areas 6,7 . Many studies have been conducted to enhance the mechanical properties of hydrogels by optimizing their network structure, including double networks, 8–11 topological networks 12–15 and dynamic crosslinking systems 16–18 . Different dynamic molecular interaction have been used to manufacture self‐healing hydrogels, such as electrostatic interactions, 19–24 hydrogen bonding, 16,18,25 hydrophobic association interaction, 26–32 host‐guest interaction, 33 and dynamic chemical bond 34–36 .…”

Section: Introductionmentioning

confidence: 99%

Tough and self‐healing hydrophobic association hydrogels with cationic surfactant

Zhen

Bai

Sun

et al. 2021

J of Applied Polymer Sci

View full text Add to dashboard Cite

Hydrophobic association (HA) hydrogels with outstanding mechanical, rheological and recovery properties were successfully synthesized by micellar copolymerization of acrylamide with lauryl methacrylate. The synthesis occurred at room temperature and the synthesis condition was moderate by using the redox initiator system of Ammonium persulfate ‐ sodium bisulfite as initiators. Cationic surfactant (dodecyl trimethyl ammonium bromide) was utilized to form micelles with hydrophobe, served as physical cross‐linking points in the 3D networks of hydrogels. The HA hydrogels showed a high tensile strength of 181 kPa, superior stretchability of 2300% and excellent toughness of 2.16 MJ m−3. Moreover, they owned extraordinary self‐recovery under different conditions. It is hopeful that the hydrogels with superior mechanical strength and self‐healing properties would be applied to the fields of biomedicine and engineering. Meanwhile, based on above materials, HA hydrogels could also be synthesized with the combination of hydrophobic association and other synergistic effects, such as latex particles, electrostatic effect and nanoparticles.

show abstract

4D Printing of Multi‐Responsive Membrane for Accelerated In Vivo Bone Healing Via Remote Regulation of Stem Cell Fate

You

Chen

Liu

et al. 2021

Adv Funct Materials

Self Cite

View full text Add to dashboard Cite

Dynamic regulation of substrate micro‐structures is an effective strategy to control stem cell fate in tissue engineering. Translating this into in vivo tissue repair in a clinical setting remains challenging, which requires precise temporal control of multi‐scale structural features. Using 4D printing technique, a multi‐responsive bilayer morphing membrane consisting of a shape memory polymer (SMP) layer and a hydrogel layer, is fabricated. The SMP layer is featured with responsive surface micro‐structures, which can switch the phase between proliferation and differentiation precisely, thus promoting the bone formation. The hydrogel layer endows the membrane with the ability to digitally regulate its 3D geometry, matching the specific macroscopic bone shape in clinical scenario. The authors’ in vivo experiments show that the 4D shape‐shifting membrane exhibits over 30% improvement in new bone formation in comparison to a reference membrane with static micro‐structure. More importantly, the 4D membrane can conformally wrap a bone defect model in a non‐invasive way and this strategy can be extended to repairs involving complex tissue defects.

show abstract

Light-triggered topological programmability in a dynamic covalent polymer network

Cited by 97 publications

References 39 publications

On demand shape memory polymer via light regulated topological defects in a dynamic covalent network

On demand shape memory polymer via light regulated topological defects in a dynamic covalent network

Tough and self‐healing hydrophobic association hydrogels with cationic surfactant

4D Printing of Multi‐Responsive Membrane for Accelerated In Vivo Bone Healing Via Remote Regulation of Stem Cell Fate

Contact Info

Product

Resources

About