Lignan production inDaphne odora cell cultures

Efficacy of Daphne oleoides subsp. kurdica used for wound healing: Identification of active compounds through bioassay guided isolation technique

“…Phytochemical studies have revealed that Daphne species contain a wide range of phytochemicals including flavonoids, coumarins, lignans, sesquiterpenes, diterpenes, triterpenes and steroids (Murray et al, 1982;Baba et al, 1986;Ulubelen et al, 1986;Kreher et al, 1990;Niwa et al, 1991;Ullah et al, 1998;Taninaka et al, 1999;Ullah, 1999;Okunishi et al, 2002). Various biological activities were also reported for Daphne species including analgesic, anti-inflammatory, antioxidant, anticancerogenic, antimicrobial, anti-ulcerogenic, abortive, hypocholesterolemic and hemostatic (Murakami et al, 1992;Cottiglia et al, 2001;Hong et al, 2002;Deiana et al, 2003;Kupeli et al, 2007;Zhang et al, 2007;Zheng et al, 2007;Lee et al, 2009).…”

Metabolic analysis of the cinnamate/monolignol pathway in Carthamus tinctorius seeds by a stable-isotope-dilution method

“…(±)-[3-OC 2 H 3 ]Arctigenins (20-d 3 ) were prepared in the same manner as the preparation of (±)-arctigenins (20) 36 but with [3-OC 2 H 3 ]-4-benzyloxy-3methoxybenzyl bromide. 33 (±)-Trachelogenins (21) were prepared in the same manner as the synthesis of wikstromol 62, 63 but with (±)-b-(3,4-dimethoxybenzyl)-c-butyrolactones prepared as previously described, 64 while (±)-[3-OC 2 H 3 ]trachelogenins (21-d 3 ) were prepared exactly as that of the unlabelled (21) but with [3-OC 2 H 3 ]-4-benzyloxy-3-methoxybenzyl bromide. 33 (±)-[3-OC (7), Y = 1.09X + 0.11, 0.05-0.37 nmol range; coniferaldehyde (8), Y = 0.92X + 0.03, 0.05-0.34 nmol range; 5-hydroxyconiferaldehyde (9), Y = 0.75X + 0.04, 0.04-0.31 nmol range; sinapaldehyde (10), Y = 0.83X + 0.07, 0.08-0.58 nmol range; p-coumaryl alcohol (11), Y = 0.76X + 0.07, 0.05-0.40 nmol range; caffeyl alcohol (12), Y = 1.44X + 0.07, 0.05-0.36 nmol range; coniferyl alcohol (13), Y = 0.26X + 0.03, 0.44-3.32 nmol range; 5-hydroxyconiferyl alcohol (14), Y = 3.96X + 0.73, 0.04-0.31 nmol range; sinapyl alcohol (15), Y = 0.72X + 0.07, 0.04-0.29 nmol range; pinoresinol (16), Y = 2.71X + 0.73, 0.28-2.09 nmol range; lariciresinol (17), Y = 1.31X + 0.36, 0.28-2.08 nmol range; secoisolariciresinol (18), Y = 0.87X + 0.14, 2.20-16.56 nmol range; matairesinol (19) -d 3 ) (0.4 mg each) were dissolved in 0.1 M KPB buffer (pH 7.0, 400.0 ll), and incubated individually with four maturing seeds (7 and 13 DAF) for 24 h. Then, the seeds were freeze-dried, powdered using a mortar and pestle, and extracted with hot MeOH.…”

Daphne odora Exerts Depigmenting Effects via Inhibiting CREB/MITF and Activating AKT/ERK-Signaling Pathways

“…Daphne odora , belonging to the red bean flower family, is characterized by the presence of daphnetin, daphnin, daphnodorin, umbelliferone, (+)-pinoresinol, (−)-lariciresinol, larieiresinol, (−)-secoisolariciresinol, matairesinol, and (−)-wikstromol [ 26 ]. In this investigation, daphnetin, one of the constituents of Daphne odora , accounted for 0.047% of DOE, and effectively inhibited in vitro tyrosinase activity.…”