Limitations of carbon dioxide lasers for treatment of port-wine stains

Gemert, M.J. van

doi:10.1001/archderm.123.1.71

Cited by 13 publications

(4 citation statements)

References 15 publications

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“…Experimental [1][2][3][4] and analytical [5][6][7][8] efforts have led to the adoption of lasers with wavelengths in the green -orange spectrum, pulse durations in the range of 0.1 to 10 milliseconds, and large (3-10 mm) spotsizes. Although the avoidance of scarring and dispigmentation has improved, many patients still have unacceptable or incomplete fading of their PWS.…”

Section: Introductionmentioning

confidence: 99%

Optical Monte Carlo modeling of a true port wine stain anatomy

Barton¹,

Pfefer²,

Welch³

et al. 1998

Opt. Express

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A unique Monte Carlo program capable of accommodating an arbitrarily complex geometry was used to determine the energy deposition in a true port wine stain anatomy. Serial histologic sections taken from a biopsy of a dark red, laser therapy resistant stain were digitized and used to create the program input for simulation at wavelengths of 532 and 585 nm. At both wavelengths, the greatest energy deposition occurred in the superficial blood vessels, and subsequently decreased with depth as the laser beam was attenuated. However, more energy was deposited in the epidermis and superficial blood vessels at 532 nm than at 585 nm. 934-942 (1996).

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Section: Introductionmentioning

confidence: 99%

Optical Monte Carlo modeling of a true port wine stain anatomy

Barton¹,

Pfefer²,

Welch³

et al. 1998

Opt. Express

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“…Owing largely to its absorption by intracellular and extracellular water, which predictably limits its depth of penetration, 49 this laser has also been previously used in its vaporiza‐tional mode of operation to treat some port‐wine stains 50,51 . Although not indicated for treating macular port‐wine stains and those found in children, 52 the CO 2 laser can be a useful tool in the removal of surface irregularities which result from the progressive dilatation of the blood vessels that occurs with aging. If satisfactory lightening of the port‐wine stain has not been accomplished once the hypertrophic soft tissue component has been eliminated, the residual small blood vessels can be selectively photocoagulated with use of one of the previously described visible light laser systems.…”

Section: The Evolution Of Laser Therapy For Port‐wine Stainsmentioning

confidence: 99%

Treatment of Port‐Wine Stains for the 1990s

Wheeland

1993

The Journal of Dermatologic Surgery and Oncology

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“…Histopathological analysis of PWS reveals a normal epidermis overlying an abnormal plexus of benign vascular malformations consist of ectatic capillaries of diameters varying from 10 to 300 μm. Laser treatment of PWS started in the late 1960s with continuous-wave lasers such as carbon-dioxide and argon lasers (Gemert et al, 1987;Dixon et al, 1984). During the laser treatment, light is absorbed by hemoglobin (Hb) and oxyhemoglobin (HbO 2 ) (the principle chromophores for light absorption in human tissue) within the blood vessels and then converted into heat which damages the endothelium and surrounding vessel walls (Alora & Anderson, 2000).…”

Section: Introductionmentioning

confidence: 99%