Linear lesions in myocardium created by Nd:YAG laser using diffusing optical fibers: In vitro and in vivo results

Fried, Nathaniel M.; Lardo, Albert C.; Berger, Ronald D.; Calkins, Hugh; Halperin, Henry R.

doi:10.1002/1096-9101(2000)27:4<295::aid-lsm2>3.0.co;2-t

Cited by 31 publications

(15 citation statements)

References 32 publications

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“…For this particular reflector, the maximum intensity is achieved at a distance of 3.9 mm. This means that for AF operations, we can use a laser whose output power is eight times lower (10 W instead of 80 W) than demonstrated in recent studies related to side-emitting diffusers [17,18].…”

Section: Flexible Reflectormentioning

confidence: 95%

Fiber photo-catheters for laser treatment of atrial fibrillation

Peshko

Rubtsov

Vesselov

et al. 2007

Optics and Lasers in Engineering

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A fiber photo-catheter has been developed for surgical treatment of atrial fibrillation with laser radiation. Atrial fibrillation (AF) is a heart rhythm abnormality that involves irregular and rapid heartbeats. Recent studies demonstrate the superiority of treating AF disease with optical radiation of the near infrared region. To produce long continuous transmural lesions, solid-state lasers and laser diodes, along with end-emitting fiber catheters, have been used experimentally. The absence of side-emitting flexible catheters with the ability to produce long continuous lesions limits the further development of this technology. In this research, a prototype of an optical catheter, consisting of a flexible 10-cm fiber diffuser has been used to make continuous photocoagulation lesions for effective maze procedure treatments. The system also includes: a flexible optical reflector; a series of openings for rapid self-attachment to the tissue; and an optional closed-loop irrigating chamber with circulating saline to cool the optical diffuser and irrigate the tissue.

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Section: Flexible Reflectormentioning

confidence: 95%

Fiber photo-catheters for laser treatment of atrial fibrillation

Peshko

Rubtsov

Vesselov

et al. 2007

Optics and Lasers in Engineering

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“…In contrast, other studies have demonstrated transmural linear lesions in the canine with a 50‐W Nd‐YAG laser (1064 nm; “infrared”) without char formation or endocardial tissue disruption when applying lesions in a controlled setting. Additionally, further studies have shown that when there is inadequate contact, laser energy may generate more coagulum 24 …”

Section: Energy Sourcesmentioning

confidence: 99%

“…The ability of some laser (mostly infra‐red) ablation catheters to provide very good lesion depth control may make them superior to RF energy for ventricular arrhythmias. Multiple animal models clearly demonstrate the ability of laser to provide sharp deep myocardial lesions without endocardial disruption 22–24 . In humans, the use of laser for ventricular arrhythmias has been used more in the operating room during or following revascularization rather than percutaneously 20 .…”

Section: Arrhythmia‐specific Therapiesmentioning

confidence: 99%

“…Additionally, further studies have shown that when there is inadequate contact, laser energy may generate more coagulum. 24 The use of a beam splitter has also allowed for the creation of a laser balloon designed for PVI. Guided by fluoroscopy and intracardiac echocardiography, a balloon is advanced into the PV and the beam splitter allows for a ring of laser energy to be produced at the PV os ( Fig.…”

Section: Lasermentioning

confidence: 99%

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Alternative Energy Sources for the Ablation of Arrhythmias

Cummings

Pacifico

Drago

et al. 2005

Pacing Clinical Electrophis

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IntroductionAs catheter-based ablative therapies of cardiac arrhythmias become standard of care, establishing and refining the tools used for these procedures has become critical. With a wide variety of energy sources now available for use in arrhythmia ablation, understanding advantages, disadvantages, and specific uses of each modality can help physicians choose the best modality to achieve a successful result. This article reviews many of the energy sources currently available and discusses each modality's potential advantages, disadvantages, and uses in a wide variety of electrophysiologic procedures.

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“…The utilization of laser in the treatment of AF is recent with, until now, only experimental studies. Fried et al [24] conducted an experimental study using the Nd:YAG LASER system through optical fibers. The authors reported transmural lesions without evidence of tissue perforation or of lesions of adjacent structures.…”

Section: Laser Raysmentioning

confidence: 99%