Lipemic plasma: a renaissance

Quality of erythrocyte concentrates derived from lipemic whole blood donations

“…The average western diet includes approximately 20-40 g of fat per meal, with an average daily intake around 75-100 g [23,24]. Acute intake of 40-50 g of fat is sufficient to result in mild to moderate lipemia [3]. Also the high percentage of donors with overweight, BMI > 25, in the group with lipemic donations (70%), which was also observed in the 'turbid plasma group' of the study by Peffer et al [2] suggest a less healthy diet or lifestyle of donors with lipemic plasma.…”

Genetic variations of CD36 and low platelet CD36 expression – a risk factor for lipemic plasma donation in Taiwanese apheresis donors

“…Besides, the turbid plasma in platelet preparations may cause problems in visual inspection of swirling phenomena or bacterial contamination . Risk factors for lipemic plasma in donors are not completely known, and most donors who provide lipemic plasma have unfavourable cardiovascular profile . Recent works provided evidence that CD36 was involved in orosensory detection of dietary fat and intestinal chylomicron formation .…”

Turbid plasma donations: Need for quantification

“…On the other hand, highly unfavorable cardiovascular profile[4] and elevated lipid levels may be the cause of such units, requiring further counseling of the donor. Additionally, as highlighted by Vassallo and Stearns, false-negative results on such turbid samples[5] may compromise the blood transfusion safety. Effect on transfusion recipients of such turbid units has not yet been studied in detail and is a gray area with regards to transfusion safety.…”