Lipid Accumulation and Hemorrhage in Livers of Laying Chickens.

Abstract

S. C. White Leghorn female chickens were subjected to a restricted-refeeding program in an attempt to induce fatty liver-hemorrhagic syndrome (FLHS) and to ascertain the relationship between hemorrhage occurrence and liver lipid content. Restricted feeding resulted in significantly (P< .01) lower liver, body and abdominal fat weights. The reduced liver weight reflected significantly (P<.01) lower water, lipid and non-lipid dry component weights. None of the hens on the restricted feeding schedules had any liver hemorrhages characteristic of FLHS; however, the control, ad tibilum-fed hens, had a 25 percent incidence rate. The restricted-ref eeding program employed did not increase the incidence of FLHS. High lipid content in the liver did not necessarily indicate FLHS, yet in some manner, lipid predisposed the liver to hemorrhage because the hemorrhage of FLHS was observed only in birds with high liver lipid values.

Comparison of the coagulation profile of Fatty Liver Haemorrhagic Syndrome-susceptible laying hens and normal laying hens

“…It has been suggested that excessive fat may disrupt liver morphology and result in weakening of the reticular framework and blood vessels in the liver (Riddell, 1997). Although it is possible that high hepatic fat content predisposes the hen to develop FLHS, equal or higher hepatic lipid content has been observed in birds without haemorrhage (Wolford and Polin, 1972;Squires and Leeson, 1988). Hence, the relationship between hepatic fat deposition and haemostatic lesions is not absolute.…”

“…The decrease in egg production and increased mortality associated with FLHS cause considerable economic loss to egg producers (Riddell, 1997). Upon postmortem examination, the hens are found to have excess abdominal and liver fat and haemorrhages of various sizes in the liver (Wolford and Polin, 1972;Leeson et al, 1995;Riddell, 1997). It has been suggested that excessive fat may disrupt liver morphology and result in weakening of the reticular framework and blood vessels in the liver (Riddell, 1997).…”

Effect of roxarsone inclusion in the diet on the performance and hepatic lipid metabolism of laying Tsaiya duck

“…The liver is the major site for lipid synthesis and fatty liver haemorrhagic syndrome (FLHS) occurs with excess lipid accumulation in the liver (Wolford and Polin, 1972). This decreases egg production and leads to death under severe conditions.…”

Estimating the genetic parameters for liver fat traits in broiler lines divergently selected for abdominal fat

“…Certain traits have been associated with FLHS; a greater prevalence of FLHS was observed in heavier birds, taking the age and phase of production into consideration (Meijering, 1979). In addition, FLHS was associated with the presence of abdominal and liver fat in chicken (Wolford and Polin, 1972), while those with lower liver fat content remained unaffected (Wolford and Polin, 1972;Crespo and Shivaprasad, 2003). Yeh et al (2009) reported a positive correlation between FLHS and liver percentage (LP).…”

“…Excessive hepatic lipid deposition in chicken can cause steatosis and fatty liver hemorrhagic syndrome (FLHS), which is characterized by obesity, an acute drop in egg production, and sudden death from hepatic rupture and hemorrhage (Wolford and Polin, 1972;Thomson et al, 2003;Yeh et al, 2009). Certain traits have been associated with FLHS; a greater prevalence of FLHS was observed in heavier birds, taking the age and phase of production into consideration (Meijering, 1979).…”