Lipid Levels in Acute Coronary Syndromes Admitted in Medical Intensive Care Unit in a Tertiary Care Hospital

Abstract

BACKGROUND Coronary artery disease (CAD) is the leading cause of mortality in men and women. Acute coronary syndrome (ACS), is a major reason for hospitalisation in our country. Dyslipidemia has been identified as one of the most important modifiable risk factors for CAD. The aim of the study was to determine the prevalence and pattern of dyslipidaemia and its relation to other modifiable risk factors. METHODS 100 cases were studied in a Krishna Institutes of Medical Sciences, Karad, over a period of 12 months from 1 st August 2015 to 31 st July 2016. This is a prospective observational study. All adults >18 years of age admitted for acute coronary syndrome were eligible for this study. The ACS group was studied as STEMI, NSTEMI, and Unstable Angina. RESULTS Majority of patients (33) was in the age group 51-60 years followed by 29 patients in the age group 61-70 years. Out of 100 ACS patients, 62 were STEMI, 20 were NSTEMI, and 18 were unstable angina. The prevalence of ACS was higher in males than females. Hypertension is the most common risk factor of ACS (41%) followed by diabetes mellitus (33%). We found that high levels of TC (more than 200 mg/dl) were found in 31% patients [mean ± SD (167.79 mg/dl ± 45.28)]. High levels of LDL (more than 130 mg/dl) were found in 23% patients [mean ± SD (97.47 mg/dl ± 38.24)]. Low levels of HDL (less than 40 mg/dl) were found in 52% patients [mean ± SD (40.69 mg/dl ± 11.84)]. High levels of TG (more than 150 mg/dl) were found in 37 % patients [mean ± SD (145.28 mg/dl ± 65.78)]. CONCLUSIONS Dyslipidemia is one of the major risk factors which is widely prevalent in patients with ACS and is more prevalent in males than in females. We recommend paying more attention to serum lipids and other modifiable risk factors for prevention of ACS

A cross-sectional study determining prevalence and factors associated with ST-segment elevation myocardial infarction and non-ST segment elevation myocardial infarction in Iran: results from fasa registry on acute myocardial infarction (FaRMI)

“…The present research also highlights the significance of lipid profiles in relation to MI risk; heightened total cholesterol, LDL cholesterol, and triglyceride concentrations correlated with an increased likelihood of experiencing STEMI/non-STEMI. These findings are consistent with previous research demonstrating an elevated dyslipidemia prevalence in patients with ACS, regardless of their obesity status [ 41 , 42 ]. These results emphasize the crucial role of lipid management in cardiovascular disease prevention and management.…”

Small Dense Low-Density Lipoprotein for Risk Prediction of Acute Coronary Syndrome

“…Secondly, confounding factors were not taken into account. Thirdly, among earlier Indian studies [21][22][23], the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) Study [24] also reported low levels of high-density lipoprotein (HDL). Hence, we did not aim to study this lipoprotein parameter.…”