Lipid profile in patients with psoriasis in Zahedan, south‐east Iran

Hashemi, Mohammad; Daliri, M; Mehrabifar, Hamid; Naderi, Mohammad; Niazi, Abbas Ali; Ghavami, Saeid

doi:10.1111/j.1468-3083.2008.02906.x

Cited by 2 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Serum total cholesterol, triglycerides and HDL-C were assessed by enzymatic methods using commercially available kits ( 27 ). LDL-C was estimated by the Friedewald formula (LDL-C ϭ total cholesterol Ϫ (HDL-C ϩ triglycerides/5)) and VLDL-C calculated by: triglycerides/5.…”

Section: Methodsmentioning

confidence: 99%

The Status of Glutathione Peroxidase, Superoxide Dismutase, Vitamins A, C, E and Malondialdehyde in Patients with Cardiovascular Disease in Zahedan, Southeast Iran

Karajibani

Hashemi

Montazerifar

et al. 2009

J Nutr Sci Vitaminol

View full text Add to dashboard Cite

Summary Growing evidence has demonstrated that oxidative stress and increased altered oxygen utilization contribute to atherogenesis and cardiovascular disease (CVD) progression. Antioxidants protect the body from damage caused by free radicals. The objective of this study was to determine antioxidants status in CVD patients. This cross-sectional study was performed on 71 patients clinically diagnosed with CVD and 63 healthy individuals. Plasma malondialdehyde (MDA) level was measured for lipid peroxidation product and erythrocyte SOD and GPx activities as enzymatic antioxidants. The serum levels of vitamins A and E were assayed using HPLC and vitamin C by the photometric method. Total antioxidant capacity (TAC) was measured using the ferric reducing ability of plasma (FRAP) method. The results showed a significant reduction in antioxidant status (enzymatic and non-enzymatic) with a concomitant increase in the concentrations of lipid peroxidation products in CVD patients. There was a significant inverse correlation among TAC, SOD, GPx and vitamin C with MDA. It can be concluded that the antioxidant defense system plays an important role in preventing the development and progression of CVD with the ability to control oxidative stress.

show abstract

Section: Methodsmentioning

confidence: 99%

The Status of Glutathione Peroxidase, Superoxide Dismutase, Vitamins A, C, E and Malondialdehyde in Patients with Cardiovascular Disease in Zahedan, Southeast Iran

Karajibani

Hashemi

Montazerifar

et al. 2009

J Nutr Sci Vitaminol

View full text Add to dashboard Cite

show abstract

Psoriasis Therapy and Cardiovascular Risk Factors

Coimbra

Oliveira

Reis

et al. 2010

American Journal of Clinical Dermatology

View full text Add to dashboard Cite

Our data show that psoriatic patients present with several lipid profile changes that seem to be related to the severity of the disease and/or the treatment used. Mild psoriasis patients receiving topical treatment presented before starting therapy with a lipid profile similar to controls, whereas those undergoing NB-UVB and PUVA, who had higher PASI scores, presented with several risk factors. Moreover, PUVA therapy seems to interact in a different way with lipids that might result from an interaction of psoralen with plasma lipids, namely Lp(a). Inflammation, a hallmark of psoriasis, also seems to be related to psoriasis severity. Both NB-UVB and PUVA were effective, as shown by the reduction in PASI score, as well as in the oxidative and inflammatory stress markers. However, after NB-UVB and PUVA, a low-grade inflammatory process still persisted, which might be related to the duration of remission of the disease.

show abstract

Lipid profile in patients with psoriasis in Zahedan, south‐east Iran

Cited by 2 publications

References 10 publications

The Status of Glutathione Peroxidase, Superoxide Dismutase, Vitamins A, C, E and Malondialdehyde in Patients with Cardiovascular Disease in Zahedan, Southeast Iran

The Status of Glutathione Peroxidase, Superoxide Dismutase, Vitamins A, C, E and Malondialdehyde in Patients with Cardiovascular Disease in Zahedan, Southeast Iran

Psoriasis Therapy and Cardiovascular Risk Factors

Contact Info

Product

Resources

About