Lipid profile of regular blood donors

Uche, EI; Adediran, Adewumi; Damulak, O D; Adeyemo, T A; Akinbami, Akinsegun; Akanmu, AS

doi:10.2147/jbm.s42211

Cited by 15 publications

(5 citation statements)

References 13 publications

(9 reference statements)

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“…This may be associated with the risk of cardiovascular disease reported by some authors, as well as with the oxidative changes caused by iron [11] . Regular blood donation may be protective against cardiovascular disease as reflected by significantly lower mean total cholesterol and low-density lipoprotein levels in regular blood donors than in non-donors [12] . Endothelial dysfunction, secondary to systemic inflammation and oxidative stress, is known to play a major role in the development and progression of atherosclerosis.…”

Section: Discussionmentioning

confidence: 97%

Assessment of levels of awareness towards blood donation in Saudi Arabia

et al. 2018

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Backgroundblood products is an interesting term as all blood and blood transfusion procedures carry risk even with advance screening of donors and donated blood. In Saudi Arabia voluntary donors are either the only source or not, the other source is paid donors and the lack of volunteers represents a major challenge. This is usually attributed to low community awareness regarding voluntary blood donation. Therefore, the objective of this study was to assess the levels of awareness towards blood donation in northern Saudi Arabia.Methodologyin this descriptive cross sectional survey, data about blood donation were obtained from 717 Saudi volunteers living in the city of Hail, Saudi Arabia. A Purposeful questionnaire was designed and used for obtaining of the necessary data.ResultsWhen asking the participants to rate the level of awareness about blood donation in Saudi Society, the majority of participants categorized the levels as good followed by very good and poor, representing 48.8%, 29.3%, and 22% participants, respectively.Conclusionthe broad concept of blood donation is still poor in Saudi Arabia. Further educational plans are needed to raise the level of awareness and increase the perception of blood donation among Saudi population. Efforts should be made to involve females in blood donation duties.

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Section: Discussionmentioning

confidence: 97%

Assessment of levels of awareness towards blood donation in Saudi Arabia

et al. 2018

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“… 20 It was shown that phlebotomy will reduce body iron stores, lower blood pressure, and reduce the risk of developing hyperglycemia and cardiovascular diseases, characteristics most often associated with obesity. 21 People with higher BMI, advanced age, and low physical activity tend to show unfavorable plasma lipid profile that may predispose them to cardiovascular diseases. Thus, obese people may have greater inclination to donate blood because of these benefits.…”

Section: Discussionmentioning

confidence: 99%

Medical and laboratory assessment for regular blood donors in Sulaimani Blood Bank, Iraq

Getta¹,

Ahmad²,

Rahman³

et al. 2018

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IntroductionIt has been suggested that blood donation reduces risks of developing cardiovascular diseases such as heart failure, atherosclerosis, and stroke. Although there are known benefits of blood donation, the inclination of people of the Kurdistan Region of Iraq to donate blood is not known. Therefore, the aim of this study was to determine demograpic and blood biochemical profiles of regular and first-time blood donors in the Sulaimani province of North Iraq.MethodsA cross-sectional study was conducted at the Sulaimani Blood Bank, during the period of April 1, 2016 to March 28, 2017, on convenient samples of 100 regular and 100 first-time blood donors. Donor particulars were obtained from blood bank records. The cholesterol, triglyceride, low-density lipoprotein, ferritin, vitamin D3, and uric acid concentrations of blood samples were determined.ResultsThe main reason for blood donation by regular blood donors was headache (45%), while for the first-timers it was to help relatives (31%). The low-density lipoprotein and ferritin concentrations were significantly (p=0.001) lower in the blood of regular donors than first-timers.ConclusionThe study shows that regular blood donation is beneficial for the maintenance of health of donors.

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“…Our study population was relatively healthy, with respect to both blood lipid levels and physical activity, which is probably the result of donor selection based on eligibility criteria and self-selection [53–56]. Beneficial effects of repeated blood donation on blood lipid profiles have been suggested in the literature [57, 58]. However, in these studies, active donors were compared with new and former donors [57, 58].…”

Section: Discussionmentioning

confidence: 99%

“…Beneficial effects of repeated blood donation on blood lipid profiles have been suggested in the literature [57, 58]. However, in these studies, active donors were compared with new and former donors [57, 58]. As such, self-selection of donors may have caused considerable confounding.…”

Section: Discussionmentioning

confidence: 99%

The association between population density and blood lipid levels in Dutch blood donors

et al. 2019

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BackgroundIn low and middle-income countries (LMIC), the total and LDL cholesterol and triglyceride levels of residents of urban areas are reported to be higher than those of rural areas. This may be due to differences in lifestyle behaviors between residents of urban areas and rural areas in LMIC. In this study, our aims were to (1) examine whether or not LDL cholesterol, total/HDL ratios and triglyceride levels of individuals in densely populated areas are higher than those of individuals living in less-densely populated areas in a high-income country (HIC) and (2) investigate the potential mediating roles of physical activity and sedentary behavior.MethodsWe used cross-sectional data from 2547 Dutch blood donors that participated in Donor InSight-III. Linear regression was used to analyze the association between population density and LDL cholesterol, total/HDL cholesterol ratio and HDL cholesterol. The mediating roles of moderate-to-vigorous physical activity (MVPA) and sedentary behavior were investigated in a subsample (n = 740) for which objectively measured MVPA/sedentary behavior data was available. Multiple mediation with linear regression analyses were performed and the product-of-coefficients method was used to calculate direct and indirect effects.ResultsMean LDL cholesterol and median total cholesterol/HDL cholesterol ratio and triglyceride levels were 2.89, 3.43 and 1.29 mmol/L, respectively. Population density was not associated with LDL cholesterol [β 0.00 (− 0.01; 0.01)], log transformed total/HDL cholesterol ratio [β 1.00 (1.00; 1.00)] and triglyceride levels [β 1.00 (0.99; 1.00)]. No statistically significant direct or indirect effects were found.ConclusionContrary to previous findings in LMIC, no evidence was found that population density is associated with blood lipid levels in blood donors in the Netherlands or that MVPA and sedentary behavior mediate this association. This may be the result of socioeconomic differences and, in part, may be due to the good health of the study population and the relatively high population density in the Netherlands. Also, compared to LMIC, differences in physical activity levels in more versus less populated areas may be less pronounced in HIC.Electronic supplementary materialThe online version of this article (10.1186/s12942-019-0167-y) contains supplementary material, which is available to authorized users.

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Lipid profile of regular blood donors

Cited by 15 publications

References 13 publications

Assessment of levels of awareness towards blood donation in Saudi Arabia

Assessment of levels of awareness towards blood donation in Saudi Arabia

Medical and laboratory assessment for regular blood donors in Sulaimani Blood Bank, Iraq

The association between population density and blood lipid levels in Dutch blood donors

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