Lipopolysaccharide (LPS) introduction during growth and development period of rat’s tooth toward the occurrence of enamel hypoplasia

Indahyani, Didin Erma; Santoso, Al-Supartinah; Utoro, Totok; Soesatyo, Marsetyawan Hne

doi:10.20473/j.djmkg.v40.i2.p85-88

Cited by 3 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…LPS induces the production of local factors, namely pro-inflammatory cytokines such as interleukin-1α (IL-1α), IL-1β, tumor necrosis factor-α (TNF-α), and eicosanoids, including prostaglandin E2 (PGE2). Prostaglandins and proinflammatory cytokines promote destruction of periodontal tissue by stimulating osteoclast production and activity and decreasing the numbers and activity of osteoblasts [6]. Umezu et al revealed that mice injected with E. coli LPS in the mucosal region of the maxillary first molar exhibit alveolar bone resorption caused by excessive osteoclast numbers and activity.…”

Section: Introductionmentioning

confidence: 99%

Aloe Vera Ethanol Extract as a Therapy for Alveolar Mandible Regeneration in Lipopolysaccharide-Exposed Rats

et al. 2018

View full text Add to dashboard Cite

Objective:The study examined the effects of Aloe vera ethanol extract on alveolar mandible regeneration in rats (Rattus norvegicus).Methods: Rats were divided into five groups as follows: Negative control group received no treatment, positive control group received Escherichia coli lipopolysaccharide (LPS) alone for 5 days, and Groups P1, P2, and P3 received LPS for 5 days followed by 40, 80, and 160 mg/kg BW A. vera ethanol extract, respectively, orally on days 6-12. Alveolar bone tissues were taken and histologically processed through hematoxylin-eosin staining. Osteoblast and osteoclast numbers in alveolar tissue were also examined. Results:One-way ANOVA revealed strong relationships between the A. vera ethanol extract dosage and the numbers of osteoblasts (r=0.921, p<0.05) and osteoclasts (r=−0.631, p<0.05) in rats. Conclusion:A. vera ethanol extract appears capable of stimulating alveolar bone regeneration following LPS exposure.

show abstract

Section: Introductionmentioning

confidence: 99%

Aloe Vera Ethanol Extract as a Therapy for Alveolar Mandible Regeneration in Lipopolysaccharide-Exposed Rats

et al. 2018

View full text Add to dashboard Cite

show abstract

How prenatal environmental factors affect rat molar enamel formation?

2022

View full text Add to dashboard Cite

Minyak ikan Lemuru (Sardinella longicep) menurunkan apoptosis osteoblas pada tulang alveolaris tikus wistar (Fish oil of Lemuru (Sardinella longicep) reduced the osteoblast apoptosis in wistar rat alveolar bone)

Lipopolysaccharide (LPS) introduction during growth and development period of rat’s tooth toward the occurrence of enamel hypoplasia

Abstract: The aim of this study is to know the effect of lipopoly saccharide (LPS)

Cited by 3 publications

References 13 publications

Aloe Vera Ethanol Extract as a Therapy for Alveolar Mandible Regeneration in Lipopolysaccharide-Exposed Rats

Aloe Vera Ethanol Extract as a Therapy for Alveolar Mandible Regeneration in Lipopolysaccharide-Exposed Rats

How prenatal environmental factors affect rat molar enamel formation?

Minyak ikan Lemuru (Sardinella longicep) menurunkan apoptosis osteoblas pada tulang alveolaris tikus wistar (Fish oil of Lemuru (Sardinella longicep) reduced the osteoblast apoptosis in wistar rat alveolar bone)

Contact Info

Product

Resources

About