Liposarcoma of the retropharyngeal space with rapidly worsening dyspnea: A case report and review of the literature

He, Jian‐Guo; Jiang, Hua; Yang, Baoyu; Lin, Peipei

doi:10.3892/ol.2013.1310

Cited by 8 publications

(8 citation statements)

References 16 publications

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“…6 Guo et al also reported a similar case with extensions from the level of the hyoid bone to the superior margin of the mediastinum, where the mass displaced trachea and larynx anteriorly and carotid arteries laterally. 7 In his report just like our case, FNAC showed features that suggested of lipoma, but after excision histopathology diagnosed it as well-differentiated liposarcoma. Azeem et al reported a similar case in the oropharynx but was extending into the oral cavity with the same clinical features and extensions.…”

Section: Discussionsupporting

confidence: 56%

“…JG et al in his study mentioned that under microscopy, the lesion had components of mature adipocytes and lipoblasts with nuclear atypia. 7 Azeem et al in his case report revealed a well-encapsulated tumor consisting predominantly of myxoid stroma with few mature fat cells, lipoblasts and floret cells suggesting myxoid liposarcoma. 8 In our case, complete excision of the tumor was done through transcervical approach.…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

A rare case of atypical lipoma in retropharyngeal space and review of literature

Narayana

Mohiyuddin

Viswambharan

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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<p class="abstract">The term atypical lipoma was introduced to describe the relatively benign course of well-differentiated liposarcomas when they occur in extremities compared to their retroperitoneal counterparts. A 32-year-old lady presented with dysphagia, excessive snoring and difficulty in breathing for three months<span>. On examination, a smooth globular retropharyngeal swelling was seen extending anteriorly till epiglottis obscuring the view of vocal cords. The CECT scan demonstrated features suggestive of a lipomatous lesion with possible sarcomatous change. Excision was done through a transcervical approach and histopathology showed features suggestive of atypical lipoma of retropharyngeal space</span>. As the tumor was removed in toto, adjuvant radiotherapy was not advised. Hence if any swelling in the retropharyngeal space is noted, the probability of soft tissue tumors must be ruled out by a CT/MRI scan before attempting incision and drainage or any other surgical procedure. Postoperative adjuvant radiotherapy is limited to high-grade tumors, incompletely excised tumors and more radiosensitive liposarcoma subtypes such as myxoid sarcomas.</p>

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Section: Discussionsupporting

confidence: 56%

Section: Discussionmentioning

confidence: 94%

A rare case of atypical lipoma in retropharyngeal space and review of literature

Narayana

Mohiyuddin

Viswambharan

et al. 2019

Int J Otorhinolaryngol Head Neck Surg

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“…Myxoid LS occurs predominantly in the extremities of young adults and has a disproportionately high tendency to metastasize to unusual soft tissue locations, before giving pulmonary metastasis or disseminated spread. Some authors have described cases of myxoid LS in the retropharyngeal space [ 9 ], in the right inguinal region presenting as painless inguinal mass [ 10 ], in the breast [ 11 ], and in the spermatic cord manifesting as painless scrotal or inguinal mass [ 12 ] and a primary localization in the pericardium [ 13 ]. Other sites of metastasis may be bones, thyroid gland [ 14 ], neck, small bowel [ 15 ], pericardium, and heart and in very rare cases myxoid LS may metastasize into the pancreas [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment

Grasso¹,

Marino²,

Bottalico³

et al. 2014

Case Reports in Surgery

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Retroperitoneal sarcomas are rare neoplasms that account for only 1%-2% of all solid tumors and liposarcomas represent the most frequent histological type. We describe the case of a 44-year-old female with a retroperitoneal myxoid liposarcoma of 22 × 19 × 8 cm in size. The only symptoms were persistent pain and progressive tenderness of the abdomen lasting for two months. The mass was radically excised during laparotomy. CT and MRI were useful to clarify the site of origin of the tumor, relationships with other organs, and planning surgery but final diagnosis was based on histological findings. Here we review the literature about the challenging diagnosis, treatment, and prognostic factors of this disease.

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“…The finding of a thick fibrous septum (>2 mm) on gadolinium-enhanced magnetic resonance images can accurately differentiate WDLS from benign lipoma [9] . However, the appearance of a benign lipoma may be more complex than that of a WDLS, in which case the difference cannot be distinguished radiologically [10] . Imaging studies in our case showed that the fibrous septum of the tumor was dense at the level of the larynx ( Fig.…”

Section: Discussionmentioning

confidence: 99%

Value of intraoperative pathological diagnosis in decision-making regarding resection of well-differentiated retropharyngeal liposarcoma: A case report

Ikeda

Fujii

Morishita

et al. 2021

International Journal of Surgery Case Reports

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Introduction and importance Preoperative diagnosis of well-differentiated liposarcoma (WDLS) in the retropharyngeal space is challenging because of the difficulty in obtaining a biopsy tissue specimen that will yield the microscopic findings necessary for a definitive pathological diagnosis. This report describes a case of retropharyngeal WDLS that was successfully diagnosed intraoperatively, which allowed radical resection. Case presentation The patient was a 60-year-old man suspected of having a lipomatous tumor in the retropharyngeal space. On imaging, the tumor contained linear septum-like structures that were prominent behind the larynx. Pathological examination was performed using fine-needle aspiration cytology and core needle biopsy specimens. However, no malignant features were found. Given that partial biopsy of the retropharyngeal tumor by puncture was anatomically limited, we decided to collect appropriate tissue specimens for intraoperative pathological examination. During the operation, we biopsied the tumor, including the hard portion behind the larynx, anticipating inclusion of the septum-like structures seen on imaging. A pathological diagnosis of WDLS was successfully made and the tumor was completely excised. Clinical discussion The fibrous septum with induration is important for intraoperative diagnosis of WDLS. The fibrous septum within the tumor was palpable as a rubbery hard portion. Conclusion WDLS in the retropharyngeal space could be successfully resected surgically by making a rapid intraoperative pathological diagnosis using appropriately selected tissue sampled from a hard portion of the tumor.

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Liposarcoma of the retropharyngeal space with rapidly worsening dyspnea: A case report and review of the literature

Cited by 8 publications

References 16 publications

A rare case of atypical lipoma in retropharyngeal space and review of literature

A rare case of atypical lipoma in retropharyngeal space and review of literature

A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment

Value of intraoperative pathological diagnosis in decision-making regarding resection of well-differentiated retropharyngeal liposarcoma: A case report

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