LIPOSOMAL ENCAPSULATED Zn-DTPA FOR REMOVING INTRACELLULAR 169Yb*

Cress, Edgar A.; Byrd, B.L.; Washburn, Lee C.; Snyder, Fred

doi:10.1097/00004032-198012000-00006

Cited by 12 publications

(1 citation statement)

References 9 publications

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“…From a detoxication point of view, it is interesting to note that injection of Ca2+or Zn2+-DTPA has been proven to be effective in removing Yb (70,71), Sc (72), and Ce (73) from the body. Liposome-encapsulated DTPA seems to be more effective than DTPA itself (70,71). Injection of either Na+2, Ca2+-EDTA or Na+3, Ca2+-DTPA into Yb-exposed rat mothers has been proven to be effective in reducing the transfer ofYb to their offspring (69).…”

Section: Exposure To Rare Earthsmentioning

confidence: 99%

Exposure, metabolism, and toxicity of rare earths and related compounds.

Hirano

Suzuki

1996

Environ Health Perspect

350

120

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For the past three decades, most attention in heavy metal toxicology has been paid to cadmium, mercury, lead, chromium, nickel, vanadium, and tin because these metals widely polluted the environment. However, with the development of new materials in the last decade, the need for toxicological studies on those new materials has been increasing. A group of rare earths (RE) is a good example. Although some RE have been used for superconductors, plastic magnets, and ceramics, few toxicological data are available compared to other heavy metals described above. Because chemical properties of RE are very similar, it is plausible that their binding affinities to biomolecules, metabolism, and toxicity in the living system are also very similar. In this report, we present an overview of the metabolism and health hazards of RE and related compounds, including our recent studies.ImagesFigure 1. AFigure 1. BFigure 1. C

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Section: Exposure To Rare Earthsmentioning

confidence: 99%