Despite recent sociological research exploring how stratification systems impinge on the health of socially disadvantaged populations, Black women's mental health is rarely a topic of investigation among scholars of medical sociology, sociology of race and racism, or sociology of gender. In this review, we incorporate perspectives from sociology, social psychiatry, psychology, and social work to develop a transdisciplinary intersectional model of Black women's mental health. We also present critical interventions in the extant literature. First, though stress exposure is generally associated with poor mental health, more research is necessary to ascertain the gendered-racialized stressors to which Black women are exposed, owing to their racial and gender oppression. Second, we admonish mental health scholars to incorporate other status dimensions (e.g., nativity, sexual orientation, age) to provide a more nuanced depiction of Black women's psychological health. Third, the unique and enduring relationship between the U.S. punishment system and the mental health of Black women should be further explicated in future research. Last, we envision a body of work on Black women's mental health that captures the ways in which they cope with societal level marginalization, as these forms of resilience and resistance may be mental health protective.