2005
DOI: 10.1097/01.rhu.0000158551.39738.de
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Listeria monocytogenes Septic Arthritis in a Patient Treated With Etanercept for Rheumatoid Arthritis

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Cited by 20 publications
(9 citation statements)
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“…Listeriosis in patients treated with TNF inhibitors can present as septic arthritis [77,80,81], meningitis [82,83] or sepsis [79,84]. Slifman et al .…”
Section: Specific Infections Under Biological Therapymentioning
confidence: 99%
“…Listeriosis in patients treated with TNF inhibitors can present as septic arthritis [77,80,81], meningitis [82,83] or sepsis [79,84]. Slifman et al .…”
Section: Specific Infections Under Biological Therapymentioning
confidence: 99%
“…Patients treated with IFX or etanercept are at risk for a severe course of food-borne infections with Listeria or Salmonella. Listeria can cause relatively mild gastroenteritis, but in IFX patients arthritis,3133 meningitis,3436 bacteraemia with terminal ileitis37 and sepsis have been reported 38 39. Salmonella infection can cause septic arthritis,40 but invasive systemic infections can develop due to immunosuppressive treatment, some with fatal outcomes 4143.…”
Section: Adult Literaturementioning
confidence: 99%
“…Un'attenta e recente review della letteratura ha inoltre evidenziato come spesso i dati di molti studi siano incompleti e non controllati e di come probabilmente non vi sia un reale aumento d'incidenza di infezioni gravi nei pazienti trattati con farmaci anti TNFα rispetto a quelli trattati con i DMARDs (38). Il nostro studio ha rilevato come, in oltre 600 pazienti trattati nel nostro centro con farmaci biologici, vi sia un numero modesto di casi di AS (5 casi) dovuti non solo a batteri Gram positivi, ma anche a microrganismi intracellulari come il M. tubercolosis e la L. monocytogenes; confermando, in accordo con la letteratura (39)(40)(41)(42)(43), il ruolo chiave del TNFα nella difesa contro tali microrganismi.…”
Section: Discussioneunclassified