Listerien-Endophthalmitis

Berger, E.; Donat, M.; Guthoff, Rudolf; Podbielski, Andreas

doi:10.1007/s00347-004-1124-z

Cited by 11 publications

(9 citation statements)

References 4 publications

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“…To date, all cases of L. monocytogenes endophthalmitis have been presumed to be endogenous,2,6,7,9,12,14 although L. monocytogenes has the ability to penetrate intact conjunctival and corneal epithelium. The pathogenesis of bacterial infection often involves a compromised epithelial surface, because an intact epithelium is an effective barrier to most organisms.…”

Section: Discussionmentioning

confidence: 99%

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Listeria monocytogenes endophthalmitis following keratoconjunctivitis

Shoughy

Tabbara²

2014

OPTH

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Endophthalmitis due to endogenous or exogenous bacteria is a rare infection of the eye. We report a case of endophthalmitis following Listeria monocytogenes keratoconjunctivitis in a 27-year-old healthy white male presenting with hand motion visual acuity, right eye mucopurulent conjunctivitis, elevated intraocular pressure, and pigmented hypopyon 6 months post-keratectomy. The conjunctivitis was unresponsive to a 5-day course of topical tobramycin eye drops, and the patient developed keratitis with pain that progressed to endophthalmitis after 21 days. Diagnostic B-scan revealed vitreous exudates. Intraocular fluid specimen showed Gram-positive organisms and the aqueous culture grew penicillin-/aminoglycoside-sensitive L. monocytogenes. The patient was given intravitreal and systemic vancomycin and ceftazidime. The eye was unresponsive to intravenous penicillin and gentamicin; the anterior chamber progressively flattened and developed phthisis bulbi. L. monocytogenes keratoconjunctivitis may lead to bacterial endophthalmitis. Prompt culture and early antibiotic therapy are recommended.

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Section: Discussionmentioning

confidence: 99%

“…Since the first case of endophthalmitis due to L. monocytogenes , reported by Goodner and Okumoto in 1967,13 several cases of L. monocytogenes -induced endophthalmitis have been reported 6,12,14…”

Section: Introductionmentioning

confidence: 99%

Listeria monocytogenes endophthalmitis following keratoconjunctivitis

Shoughy

Tabbara²

2014

OPTH

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“…Because of early, aggressive antibiotic use, our patient recovered uneventfully and did not develop the endophthalmitis that routinely plagued similar cases depicted in the literature. Various authors share the opinion that early treatment confers the best prognosis with respect to preserving visual acuity [6]. …”

Section: Discussionmentioning

confidence: 99%

Fulminant Endogenous Anterior Uveitis due to Listeria monocytogenes

Hueber¹,

Welsandt²,

Grajewski³

et al. 2010

Case Rep Ophthalmol

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Purpose: To report an unusual case of fulminant anterior uveitis, confirmed as endogenous Listeria monocytogenes infection. Subject: A 67-year-old man with multiple comorbidities acutely developed a severe endogenous anterior uveitis. Results:L. monocytogenes, a ubiquitous Gram-positive bacillus, was directly indicated by culture and PCR. Early and aggressive treatment with intravenous antibiotics likely prevented the endophthalmitis which most cases on record experienced. Our patient regained satisfactory visual acuity. Conclusions: Prompt antimicrobial therapy is paramount when severe endogenous uveitis develops in a patient with comorbidities, especially with systemic immunosuppression. Treatment solely with corticosteroids should be avoided.

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“…Listeria-monocytogenes-Endophthalmitis nach intermediärer Uveitis und PPV bei Ablatio retinae Almost all cases showed similar clinical features as in the case reported here, including poor visual outcome, elevated intraocular pressure and fibrinoid anterior chamber reaction. Several patients developed a dark hypopyon [7]. The diagnosis is made only after classical culture techniques which takes several days and may delay proper antibiotic treatment.…”

Section: Listeria Monocytogenes Endophthalmitis After Intermediate Uvmentioning

confidence: 99%