2019
DOI: 10.18863/pgy.384067
|View full text |Cite
|
Sign up to set email alerts
|

Lithium Associated Side Effects and Neurotoxicity: Is Lithium Neurotoxicity Related to Iron Deposition?

Abstract: Lithium is a mood stabilizer that Australian psychiatrist John Cade and the Swiss Baastrup and Schou's pioneering studies brought in the treatment of bipolar disorder. In current guidelines, it is still considered as first line therapy for acute mania, depression and remission periods. Along with numerous neurotrophic and cytoprotective effects, lithium may rarely cause neurotoxicity. Neuro-toxicity might be related with dose dependent or independent. Mechanism of neurotoxicity has not been identified yet. A p… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 272 publications
(102 reference statements)
0
1
0
Order By: Relevance
“…This process hinders the iron efflux from the brain cells and increases the hydroxyl radicals produced by the iron. Lithium has been implicated in various outcomes, such as its effect on the retention of fluids in the hypothalamus [81].…”
Section: Discussionmentioning
confidence: 99%
“…This process hinders the iron efflux from the brain cells and increases the hydroxyl radicals produced by the iron. Lithium has been implicated in various outcomes, such as its effect on the retention of fluids in the hypothalamus [81].…”
Section: Discussionmentioning
confidence: 99%