Lithium: Environmental Pollution and Health Effects

Aral, Hal; Vecchio-Sadus, Angelica M.

doi:10.1016/b978-0-444-63951-6.00531-3

Cited by 17 publications

(18 citation statements)

References 8 publications

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“…Li concentrations ranged from the detection limit (0.01 µg/g dw) to 1.20 µg/g dw (digestive gland of Pecten maximus) (Supplementary Table S2). As the oceanic Li concentration is homogeneous at 0.18 µg/mL (Aral and Vecchio-Sadus, 2011;Misra and Froelich, 2012;Riley and Tengudai, 1964), the large range of Li concentrations observed in marine organisms must result from different bioaccumulation dynamics related to biotic and abiotic processes. To investigate this, we first examine the entire dataset to identify which factors are related to highor low -Li concentrations, and then investigate these factors in more details.…”

Section: Resultsmentioning

confidence: 99%

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Large-scale survey of lithium concentrations in marine organisms

Thibon

Weppe

Vigier

et al. 2021

Science of The Total Environment

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HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Section: Resultsmentioning

confidence: 99%

“…Thus, the oceanic concentration of dissolved Li is constant at 0.183 ± 0.003 µg/mL, irrespective J o u r n a l P r e -p r o o f of latitude and depth (Aral and Vecchio-Sadus, 2011;Misra and Froelich, 2012;Riley and Tengudai, 1964).…”

Section: Introductionmentioning

confidence: 99%

Large-scale survey of lithium concentrations in marine organisms

Thibon

Weppe

Vigier

et al. 2021

Science of The Total Environment

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“…Although Li does not have a known biological role and does not appear to be an essential element for humans, lithium salts (e.g., carbonate, acetate) have been extensively used in the treatment of manic-depressive disorders for more than 50 years [14]. In the last two decades, several studies have further suggested that Li may also have neuroprotective effects against amyotrophic lateral sclerosis, and Alzheimer's and Parkinson's diseases [15].…”

Section: Introductionmentioning

confidence: 99%

Alkali metals levels in the human brain tissue: Anatomical region differences and age-related changes

Ramos

Santos

Pinto

et al. 2016

Journal of Trace Elements in Medicine and Biology

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The link between trace elements imbalances (both "toxic" and "essential") in the human brain and neurodegenerative disease has been subject of extensive research. More recently, some studies have highlighted the potential role of the homeostasis deregulation of alkali metals in specific brain regions as key factor in the pathogenesis of neurodegenerative diseases such as multiple sclerosis and Alzheimer's disease. Using flame atomic emission spectrometry and inductively coupled plasma-mass spectrometry after microwave-assisted acid digestion of the samples, alkali metals (Na, K, Li, Rb and Cs) were determined in 14 different areas of the human brain (frontal cortex, superior and middle temporal gyri, caudate nucleus, putamen, globus pallidus, cingulated gyrus, hippocampus, inferior parietal lobule, visual cortex of the occipital lobe, midbrain, pons, medulla and cerebellum) of adult individuals (n=42; 71±12, range: 50-101 years old) with no known history and evidence of neurodegenerative, neurological or psychiatric disorder. Potassium was found as the most abundant alkali metal, followed by Na, Rb, Cs and Li. Lithium, K and Cs distribution showed to be quite heterogeneous. On the contrary, Rb and Na appeared quite homogeneously distributed within the human brain tissue. The lowest levels of Na, K, Rb and Li were found in the brainstem (midbrain, medulla and pons) and cerebellum, while the lowest levels of Cs were found in the frontal cortex. The highest levels of K (mean±sd; range 15.5±2.5; 8.9-21.8mg/g) Rb (17.2±6.1; 3.9-32.4μg/g and Cs (83.4±48.6; 17.3-220.5ng/g) were found in putamen. The highest levels of Na and Li were found in the frontal cortex (11.6±2.4; 6.6-17.1mg/g) and caudate nucleus (7.6±4.6 2.2-21.3ng/g), respectively. Although K, Cs and Li levels appear to remain largely unchanged with age, some age-related changes were observed for Na and Rb levels in particular brain regions (namely in the hippocampus).

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“…Goi-teknologiako produkzioan erabiltzen diren elementu emergenteen toxikotasunaren inguruan dagoen ezagutza oso baxua da. Lehorreko ekosistemetan, litioak gizakiengan eta beste organismo batzuengan eragin handia izan ahal duela jakinarazi da (Moore et al, 1995;Aral & Vecchio-Sadus, 2008;Aral & Vecchio-Sadus, 2011). Adibidez, arratoiek errinitis ultzeratiboa, metaplasia ezkatatsua, laringitis nekrosikoa eta arnas zailtasunak garatzen dituzte %80 litio karbonatoa duten aerosolekiko esposizioa jasatean.…”

Section: Arloko Egoera Eta Ikerketaren Helburuakunclassified

IV. Ikergazte. Nazioarteko ikerketa euskaraz. Kongresuko artikulu bilduma. Zientziak eta Natura Zientzia

2021

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Lithium: Environmental Pollution and Health Effects

Cited by 17 publications

References 8 publications

Large-scale survey of lithium concentrations in marine organisms

Large-scale survey of lithium concentrations in marine organisms

Alkali metals levels in the human brain tissue: Anatomical region differences and age-related changes

IV. Ikergazte. Nazioarteko ikerketa euskaraz. Kongresuko artikulu bilduma. Zientziak eta Natura Zientzia

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